Literature DB >> 20445502

A new vision of immunity: homeostasis of the superorganism.

G Eberl1.   

Abstract

The immune system is commonly perceived as an army of organs, tissues, cells, and molecules that protect from disease by eliminating pathogens. However, as in human society, a clear definition of good and evil might be sometimes difficult to achieve. Not only do we live in contact with a multitude of microbes, but we also live with billions of symbionts that span all the shades from mutualists to potential killers. Together, we compose a superorganism that is capable of optimal living. In that context, the immune system is not a killer, but rather a force that shapes homeostasis within the superorganism.

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Year:  2010        PMID: 20445502     DOI: 10.1038/mi.2010.20

Source DB:  PubMed          Journal:  Mucosal Immunol        ISSN: 1933-0219            Impact factor:   7.313


  60 in total

Review 1.  Immunostimulation in the era of the metagenome.

Authors:  Amy D Proal; Paul J Albert; Greg P Blaney; Inge A Lindseth; Chris Benediktsson; Trevor G Marshall
Journal:  Cell Mol Immunol       Date:  2011-01-31       Impact factor: 11.530

Review 2.  Context-dependent symbioses and their potential roles in wildlife diseases.

Authors:  Joshua H Daskin; Ross A Alford
Journal:  Proc Biol Sci       Date:  2012-01-11       Impact factor: 5.349

Review 3.  The immune system and the gut microbiota: friends or foes?

Authors:  Nadine Cerf-Bensussan; Valérie Gaboriau-Routhiau
Journal:  Nat Rev Immunol       Date:  2010-10       Impact factor: 53.106

Review 4.  Time to recognize our fellow travellers.

Authors:  Travis B Murdoch; Allan S Detsky
Journal:  J Gen Intern Med       Date:  2012-05-16       Impact factor: 5.128

5.  Immune tolerance. Group 3 innate lymphoid cells mediate intestinal selection of commensal bacteria-specific CD4⁺ T cells.

Authors:  Matthew R Hepworth; Thomas C Fung; Samuel H Masur; Judith R Kelsen; Fiona M McConnell; Juan Dubrot; David R Withers; Stephanie Hugues; Michael A Farrar; Walter Reith; Gérard Eberl; Robert N Baldassano; Terri M Laufer; Charles O Elson; Gregory F Sonnenberg
Journal:  Science       Date:  2015-04-23       Impact factor: 47.728

Review 6.  Friend, foe or food? Recognition and the role of antimicrobial peptides in gut immunity and Drosophila-microbe interactions.

Authors:  Nichole A Broderick
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2016-05-26       Impact factor: 6.237

7.  Immune balance: the development of the idea and its applications.

Authors:  Bartlomiej Swiatczak
Journal:  J Hist Biol       Date:  2014       Impact factor: 1.326

Review 8.  Microbial ecology in Hydra: why viruses matter.

Authors:  Thomas C G Bosch; Juris A Grasis; Tim Lachnit
Journal:  J Microbiol       Date:  2015-03-03       Impact factor: 3.422

9.  Enhancing the clinical coverage and anticancer efficacy of immune checkpoint blockade through manipulation of the gut microbiota.

Authors:  Jonathan M Pitt; Marie Vétizou; Ivo Gomperts Boneca; Patricia Lepage; Mathias Chamaillard; Laurence Zitvogel
Journal:  Oncoimmunology       Date:  2016-02-18       Impact factor: 8.110

Review 10.  Lymphotoxin signalling in immune homeostasis and the control of microorganisms.

Authors:  Vaibhav Upadhyay; Yang-Xin Fu
Journal:  Nat Rev Immunol       Date:  2013-04       Impact factor: 53.106

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