Literature DB >> 20443937

Pharmacotherapy and pregnancy: highlights from the Second International Conference for Individualized Pharmacotherapy in Pregnancy.

David M Haas1, Mary F Hebert, Offie P Soldin, David A Flockhart, Parvaz Madadi, James J Nocon, Christina D Chambers, Gary D Hankins, Shannon Clark, Katherine L Wisner, Lang Li, Jamie L Renbarger, Lee A Learman.   

Abstract

To address provider struggles to provide evidence-based, rational drug therapy to pregnant women, a second conference was convened to highlight the current research in the field. Speakers from academic centers and institutions spoke about: the unique physiology and pathology of pregnancy; pharmacokinetic changes in pregnancy; thyroid disorders in pregnancy; pharmacogenetics in pregnancy; the role of CYP2D6 in pregnancy; treating addiction in pregnancy; the power of teratology networks to inform clinical decisions; the use of anti-depressants in pregnancy; and how to utilize computer-based modeling to aid with individualized pharmacotherapy in pregnancy. The Conference highlighted several areas of collaboration with the current Obstetrics Pharmacology Research Units Network (OPRU) and hoped to stimulate further collaboration and knowledge in the area with the common goal to improve the ability to safely and effectively use individualized pharmacotherapy in pregnancy.

Entities:  

Mesh:

Substances:

Year:  2009        PMID: 20443937      PMCID: PMC3641763          DOI: 10.1111/j.1752-8062.2009.00166.x

Source DB:  PubMed          Journal:  Clin Transl Sci        ISSN: 1752-8054            Impact factor:   4.689


  41 in total

1.  Estimation of uterine blood flow in normal human pregnancy at term.

Authors:  J METCALFE; S L ROMNEY; L H RAMSEY; D E REID; C S BURWELL
Journal:  J Clin Invest       Date:  1955-11       Impact factor: 14.808

2.  The effect of pregnancy on gastric secretion.

Authors:  W A GRYBOSKI; H M SPIRO
Journal:  N Engl J Med       Date:  1956-12-13       Impact factor: 91.245

3.  Temporal changes in drug metabolism (CYP1A2, CYP2D6 and CYP3A Activity) during pregnancy.

Authors:  Timothy S Tracy; Raman Venkataramanan; Douglas D Glover; Steve N Caritis
Journal:  Am J Obstet Gynecol       Date:  2005-02       Impact factor: 8.661

4.  New perspectives on the benefit-cost and cost-effectiveness of drug abuse treatment.

Authors:  R L Hubbard; M T French
Journal:  NIDA Res Monogr       Date:  1991

Review 5.  Neurobiology of addiction.

Authors:  R A Wise
Journal:  Curr Opin Neurobiol       Date:  1996-04       Impact factor: 6.627

6.  Induction of CYP2D6 in pregnancy.

Authors:  M Wadelius; E Darj; G Frenne; A Rane
Journal:  Clin Pharmacol Ther       Date:  1997-10       Impact factor: 6.875

Review 7.  The regulation of thyroid function in pregnancy: pathways of endocrine adaptation from physiology to pathology.

Authors:  D Glinoer
Journal:  Endocr Rev       Date:  1997-06       Impact factor: 19.871

Review 8.  Brief interventions for alcohol problems: a review.

Authors:  T H Bien; W R Miller; J S Tonigan
Journal:  Addiction       Date:  1993-03       Impact factor: 6.526

9.  Pharmacokinetics and pharmacodynamics of atenolol during pregnancy and postpartum.

Authors:  Mary F Hebert; Darcy B Carr; Gail D Anderson; David Blough; Grace E Green; Debra A Brateng; Eric Kantor; Thomas J Benedetti; Thomas R Easterling
Journal:  J Clin Pharmacol       Date:  2005-01       Impact factor: 3.126

10.  Birth outcomes in pregnant women taking fluoxetine.

Authors:  C D Chambers; K A Johnson; L M Dick; R J Felix; K L Jones
Journal:  N Engl J Med       Date:  1996-10-03       Impact factor: 91.245

View more
  4 in total

Review 1.  Clinical trials during pregnancy: what has been done.

Authors:  Viviana Domínguez; Nuria Ramos; Abiguei Torrents; David García; Xavier Carné
Journal:  Eur J Clin Pharmacol       Date:  2011-11-11       Impact factor: 2.953

Review 2.  Physiologically-based pharmacokinetic models: approaches for enabling personalized medicine.

Authors:  Clara Hartmanshenn; Megerle Scherholz; Ioannis P Androulakis
Journal:  J Pharmacokinet Pharmacodyn       Date:  2016-09-19       Impact factor: 2.745

3.  Designing drug trials: considerations for pregnant women.

Authors:  Jeanne S Sheffield; David Siegel; Mark Mirochnick; R Phillips Heine; Christine Nguyen; Kimberly L Bergman; Rada M Savic; Jill Long; Kelly E Dooley; Mirjana Nesin
Journal:  Clin Infect Dis       Date:  2014-12-15       Impact factor: 9.079

Review 4.  Pharmacogenetics and individualizing drug treatment during pregnancy.

Authors:  David M Haas
Journal:  Pharmacogenomics       Date:  2014-01       Impact factor: 2.533

  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.