Donald G Guinee1. 1. Department of Pathology, Virginia Mason Medical Center, Seattle, Washington 98101, USA. Donald.Guinee@vmmc.org
Abstract
CONTEXT: Recent discoveries have expanded the spectrum of nonneoplastic pulmonary lymphoproliferative disorders and have provided new insights into their pathogenesis and treatment. OBJECTIVE: To review the thoracic manifestations of immunoglobulin (Ig) G4-related sclerosing disease and summarize current concepts and differential diagnosis of follicular bronchiolitis, lymphocytic interstitial pneumonitis, and nodular lymphoid hyperplasia. DATA SOURCES: Data sources include recent and old articles, cases from the personal files of the author, and cases borrowed with permission from other authors. CONCLUSIONS: Additional studies will be needed to further refine and add to observations in this evolving area of pulmonary pathology.
CONTEXT: Recent discoveries have expanded the spectrum of nonneoplastic pulmonary lymphoproliferative disorders and have provided new insights into their pathogenesis and treatment. OBJECTIVE: To review the thoracic manifestations of immunoglobulin (Ig) G4-related sclerosing disease and summarize current concepts and differential diagnosis of follicular bronchiolitis, lymphocytic interstitial pneumonitis, and nodular lymphoid hyperplasia. DATA SOURCES: Data sources include recent and old articles, cases from the personal files of the author, and cases borrowed with permission from other authors. CONCLUSIONS: Additional studies will be needed to further refine and add to observations in this evolving area of pulmonary pathology.
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