Sevim Turanli1, Abdullah Cetin. 1. Department of General Surgery, Ankara Oncology Education and Research Hospital, Demetevler, Ankara, Turkey. turanlisevim@hotmail.com
Abstract
OBJECTIVE: To investigate the association between cancer antigen (CA) 15-3 and clinicopathological parameters in patients who had breast cancer with isolated bone metastases at the time of diagnosis and to analyse the effect on clinical outcomes. METHODS: Between June 2004 and January 2007, the data of 129 consecutive patients were examined. RESULTS: Elevated CA 15-3 levels were associated with poor disease-free survival (p = 0.001) and overall survival (p = 0.006). In multivariate analysis, serum CA 15-3 level (p = 0.003) was found to be an independent factor in overall survival. CONCLUSION: Elevated CA 15-3 level is a useful parameter for predicting clinical outcomes.
OBJECTIVE: To investigate the association between cancer antigen (CA) 15-3 and clinicopathological parameters in patients who had breast cancer with isolated bone metastases at the time of diagnosis and to analyse the effect on clinical outcomes. METHODS: Between June 2004 and January 2007, the data of 129 consecutive patients were examined. RESULTS: Elevated CA 15-3 levels were associated with poor disease-free survival (p = 0.001) and overall survival (p = 0.006). In multivariate analysis, serum CA 15-3 level (p = 0.003) was found to be an independent factor in overall survival. CONCLUSION: Elevated CA 15-3 level is a useful parameter for predicting clinical outcomes.