Literature DB >> 20441050

Lentivirus-mediated knockdown of cyclin Y (CCNY) inhibits glioma cell proliferation.

YongGang Xu1, Zhi Wang, Jie Wang, JianHua Li, HongWei Wang, Wu Yue.   

Abstract

Cyclin Y (CCNY) is a novel cyclin and almost nothing is known about its expression level and role in human cancers. In the present study, we found that lentivirus-mediated RNA interference (RNAi) of CCNY significantly downregulated its expression level. More importantly, knockdown of CCNY inhibited cell proliferation, colony formation, and cell cycle progression in glioma cells. These data suggest that CCNY might play an important role in glioma tumorigenisis.

Entities:  

Mesh：

Substances：

Year:  2010        PMID： 20441050     DOI： 10.3727/096504010x12644422320582

Source DB:  PubMed          Journal:  Oncol Res        ISSN： 0965-0407            Impact factor:   5.574


  18 in total

1.  Down-regulation of ALKBH2 increases cisplatin sensitivity in H1299 lung cancer cells.

Authors:  Shuang-shuang Wu; Wei Xu; Shan Liu; Bo Chen; Xue-li Wang; Yan Wang; Shi-feng Liu; Jian-qing Wu
Journal:  Acta Pharmacol Sin       Date:  2011-01-31       Impact factor: 6.150

2.  The role of Med19 in the proliferation and tumorigenesis of human hepatocellular carcinoma cells.

Authors:  Shao-wu Zou; Kai-xing Ai; Zhi-gang Wang; Zhou Yuan; Jun Yan; Qi Zheng
Journal:  Acta Pharmacol Sin       Date:  2011-03       Impact factor: 6.150

3.  Cyclin Y regulates the proliferation, migration, and invasion of ovarian cancer cells via Wnt signaling pathway.

Authors:  Haiyuan Liu; Honghui Shi; Qingbo Fan; Xiangxiu Sun
Journal:  Tumour Biol       Date:  2016-01-29

4.  PFTK1 Promotes Gastric Cancer Progression by Regulating Proliferation, Migration and Invasion.

Authors:  Lei Yang; Jia Zhu; Hua Huang; Qichang Yang; Jing Cai; Qiuhong Wang; Junya Zhu; Mengting Shao; Jinzhang Xiao; Jie Cao; Xiaodan Gu; Shusen Zhang; Yingying Wang
Journal:  PLoS One       Date:  2015-10-21       Impact factor: 3.240

5.  Structure and inhibitor specificity of the PCTAIRE-family kinase CDK16.

Authors:  Sarah E Dixon-Clarke; Saifeldin N Shehata; Tobias Krojer; Timothy D Sharpe; Frank von Delft; Kei Sakamoto; Alex N Bullock
Journal:  Biochem J       Date:  2017-02-20       Impact factor: 3.857

6.  Cyclin Y-mediated transcript profiling reveals several important functional pathways regulated by Cyclin Y in hippocampal neurons.

Authors:  I-Seul Joe; Jong-Hwan Kim; Hanna Kim; Jung-Hwa Hong; Mirang Kim; Mikyoung Park
Journal:  PLoS One       Date:  2017-02-27       Impact factor: 3.240

7.  Cytoplasmic Localization Isoform of Cyclin Y Enhanced the Metastatic Ability of Lung Cancer via Regulating Tropomyosin 4.

Authors:  Xiaoting Zhao; Mei Jiang; Yu Teng; Jie Li; Zhefeng Li; Wende Hao; Hongyu Zhao; Chenghong Yin; Wentao Yue
Journal:  Front Cell Dev Biol       Date:  2021-06-18

8.  Cyclin Y inhibits plasticity-induced AMPA receptor exocytosis and LTP.

Authors:  Eunsil Cho; Dong-Hyun Kim; Young-Na Hur; Daniel J Whitcomb; Philip Regan; Jung-Hwa Hong; Hanna Kim; Young Ho Suh; Kwangwook Cho; Mikyoung Park
Journal:  Sci Rep       Date:  2015-07-29       Impact factor: 4.379

9.  Serum anti-CCNY autoantibody is an independent prognosis indicator for postoperative patients with early-stage nonsmall-cell lung carcinoma.

Authors:  Li Ma; Wentao Yue; Yu Teng; Lina Zhang; Meng Gu; Yue Wang
Journal:  Dis Markers       Date:  2013-09-18       Impact factor: 3.434

10.  A systematic analysis of orphan cyclins reveals CNTD2 as a new oncogenic driver in lung cancer.

Authors:  L Gasa; A Sanchez-Botet; E Quandt; S Hernández-Ortega; J Jiménez; M A Carrasco-García; S Simonetti; S J Kron; M P Ribeiro; E Nadal; A Villanueva; J Clotet
Journal:  Sci Rep       Date:  2017-08-31       Impact factor: 4.379
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.