Literature DB >> 20439357

How the distinction between "irreversible" and "permanent" illuminates circulatory-respiratory death determination.

James L Bernat1.   

Abstract

The distinction between the "permanent" (will not reverse) and "irreversible" (cannot reverse) cessation of functions is critical to understand the meaning of a determination of death using circulatory-respiratory tests. Physicians determining death test only for the permanent cessation of circulation and respiration because they know that irreversible cessation follows rapidly and inevitably once circulation no longer will restore itself spontaneously and will not be restored medically. Although most statutes of death stipulate irreversible cessation of circulatory and respiratory functions, the accepted medical standard is their permanent cessation because permanence is a perfect surrogate indicator for irreversibility, and using it permits a more timely declaration. Therefore, patients properly declared dead in donation after circulatory death (DCD) protocols satisfy the requirements of death statutes and do not violate the dead donor rule. The acronym DCD should represent organ "donation after circulatory death" to clarify that the death standard is the permanent cessation of circulation, not heartbeat. Heart donation in DCD does not retroactively negate the donor's death determination because circulation has ceased permanently.

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Year:  2010        PMID: 20439357     DOI: 10.1093/jmp/jhq018

Source DB:  PubMed          Journal:  J Med Philos        ISSN: 0360-5310


  13 in total

1.  The ethical obligation of the dead donor rule.

Authors:  Anne L Dalle Ave; Daniel P Sulmasy; James L Bernat
Journal:  Med Health Care Philos       Date:  2020-03

Review 2.  Brain death, cardiac death, and the dead donor rule.

Authors:  Robert M Sade
Journal:  J S C Med Assoc       Date:  2011-08

3.  Controversies in defining death: a case for choice.

Authors:  Robert M Veatch
Journal:  Theor Med Bioeth       Date:  2019-10

Review 4.  Controversies in defining and determining death in critical care.

Authors:  James L Bernat
Journal:  Nat Rev Neurol       Date:  2013-02-19       Impact factor: 42.937

5.  Revisiting the Persisting Tension Between Expert and Lay Views About Brain Death and Death Determination: A Proposal Inspired by Pragmatism.

Authors:  Eric Racine
Journal:  J Bioeth Inq       Date:  2015-12-01       Impact factor: 1.352

6.  Controversy in the Determination of Death: The Definition and Moment of Death.

Authors:  Frederick J White
Journal:  Linacre Q       Date:  2019-10-13

Review 7.  Normothermic Regional Perfusion is an Emerging Cost-Effective Alternative in Donation After Circulatory Death (DCD) in Heart Transplantation.

Authors:  Emad Alamouti-Fard; Pankaj Garg; Ishaq J Wadiwala; John H Yazji; Mohammad Alomari; Md Walid Akram Hussain; Mohamed S Elawady; Samuel Jacob
Journal:  Cureus       Date:  2022-06-29

8.  Donation after cardiocirculatory death: a call for a moratorium pending full public disclosure and fully informed consent.

Authors:  Ari R Joffe; Joe Carcillo; Natalie Anton; Allan deCaen; Yong Y Han; Michael J Bell; Frank A Maffei; John Sullivan; James Thomas; Gonzalo Garcia-Guerra
Journal:  Philos Ethics Humanit Med       Date:  2011-12-29       Impact factor: 2.464

9.  Donation after brain circulation determination of death.

Authors:  Anne L Dalle Ave; James L Bernat
Journal:  BMC Med Ethics       Date:  2017-02-23       Impact factor: 2.652

10.  The neuroethics of disorders of consciousness: a brief history of evolving ideas.

Authors:  Michael J Young; Yelena G Bodien; Joseph T Giacino; Joseph J Fins; Robert D Truog; Leigh R Hochberg; Brian L Edlow
Journal:  Brain       Date:  2021-12-16       Impact factor: 13.501

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