BACKGROUND:Psychosocial interventions have the potential to enhance relapse prevention in bipolar disorder. AIMS: To evaluate a manualised group-based intervention for people with bipolar disorder in a naturalistic setting. METHOD:Eighty-four participants were randomised to receive the group-based intervention (a 12-week programme plus three booster sessions) or treatment as usual, and followed up with monthly telephone interviews (for 9 months post-intervention) and face-to-face interviews (at baseline, 3 months and 12 months). RESULTS: Participants who received the group-based intervention were significantly less likely to have a relapse of any type and spent less time unwell. There was a reduced rate of relapse in the treatment group for pooled relapses of any type (hazard ratio 0.43, 95% CI 0.20-0.95; t(343) = -2.09, P = 0.04). CONCLUSIONS: This study suggests that the group-based intervention reduces relapse risk in bipolar disorder.
RCT Entities:
BACKGROUND:Psychosocial interventions have the potential to enhance relapse prevention in bipolar disorder. AIMS: To evaluate a manualised group-based intervention for people with bipolar disorder in a naturalistic setting. METHOD: Eighty-four participants were randomised to receive the group-based intervention (a 12-week programme plus three booster sessions) or treatment as usual, and followed up with monthly telephone interviews (for 9 months post-intervention) and face-to-face interviews (at baseline, 3 months and 12 months). RESULTS:Participants who received the group-based intervention were significantly less likely to have a relapse of any type and spent less time unwell. There was a reduced rate of relapse in the treatment group for pooled relapses of any type (hazard ratio 0.43, 95% CI 0.20-0.95; t(343) = -2.09, P = 0.04). CONCLUSIONS: This study suggests that the group-based intervention reduces relapse risk in bipolar disorder.
Authors: Laura A Bajor; Zongshan Lai; David E Goodrich; Christopher J Miller; Robert B Penfold; Hyungjin Myra Kim; Mark S Bauer; Amy M Kilbourne Journal: J Affect Disord Date: 2012-09-27 Impact factor: 4.839
Authors: Jonathan P Stange; Louisa G Sylvia; Pedro Vieira da Silva Magalhães; David J Miklowitz; Michael W Otto; Ellen Frank; Michael Berk; Andrew A Nierenberg; Thilo Deckersbach Journal: J Clin Psychiatry Date: 2013-03 Impact factor: 4.384
Authors: A Pfennig; J Conell; P Ritter; D Ritter; E Severus; T D Meyer; M Hautzinger; J Wolff; F Godemann; A Reif; M Bauer Journal: Nervenarzt Date: 2017-03 Impact factor: 1.214