Shinichiro Uchiyama1, Yoshisato Shibata2, Takayuki Hirabayashi3, Ban Mihara4, Naohisa Hamashige5, Kazuo Kitagawa6, Shinya Goto7, Hideki Origasa8, Kazuyuki Shimada9, Hiroyuki Kobayashi10, Mitsuhiro Isozaki10, Yasuo Ikeda11. 1. Department of Neurology, Tokyo Women's Medical University, Tokyo, Japan. Electronic address: suchiyam@nij.twmu.ac.jp. 2. Department of Cardiology, Miyazaki Medical Association Hospital, Miyazaki, Japan. 3. Department of Cardiology, Sunagawa City Medical Center, Sunagawa, Japan. 4. Department of Neurology, Institute of Brain and Vessel, Mihara Memorial Hospital, Isezaki, Japan. 5. Department of Cardiology, Chikamori Hospital, Kochi, Japan. 6. Department of Neurology, Osaka University School of Medicine, Osaka, Japan. 7. Department of Internal Medicine, Tokai University School of Medicine, Isehara, Japan. 8. Department of Biostatistics, Toyama University Graduate School, Toyama, Japan. 9. Department of Internal Medicine, Jichi Medical School, Shimono, Japan. 10. Department of Clinical Pharmacology, Tokai University School of Medicine, Isehara, Japan. 11. Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan.
Abstract
OBJECTIVE: We sought to clarify risk factor profiles and current treatment of Japanese patients with stroke, myocardial infarction (MI), and nonvalvular atrial fibrillation (NVAF) using the database of the Japan Thrombosis Registry for Atrial Fibrillation, Coronary, or Cerebrovascular Events (J-TRACE). METHODS: J-TRACE is a nationwide multicenter cooperative cohort of Japanese patients with MI, stroke, and NVAF. Baseline characteristics of 8087 Japanese patients (5804 male, average age 68.7 years) with history of stroke (n=3554), MI (n=2291), or NVAF (n=2242) were analyzed. RESULTS: History of stroke (14.7%) was more frequent than history of MI (2.6%) in patients with stroke, whereas history of stroke (6.6%) was less frequent than history of MI (7.6%) in patients with MI. In patients with NVAF, history of stroke (14.3%) was far more frequent than history of MI (3.4%). Hypertension was more frequent in stroke (74.4%) than MI (62.0%) or NVAF (57.7%), whereas hypercholesterolemia, diabetes mellitus, and cigarette smoking were more prevalent in patients with MI (56.1%, 35.1%, and 33.3%, respectively) than in those with stroke (35.7%, 22.4%, and 19.7%, respectively) or NVAF (26.9%, 17.2%, and 16.1%, respectively). Alcohol consumption (34.9%) and obesity (body mass index>25) (32.8%) were most common in patients with NVAF. In all patients, nonmedication rates were higher in patients with hypercholesterolemia (29.8%) or diabetes (36.9%) than in those with hypertension (9.5%). Warfarin was used in 58.9% of patients with low-risk and 75.4% with high-risk NVAF. CONCLUSION: Risk factor profiles and their modification were not similar among patients in Japan with MI, stroke, and NVAF, although they share a high risk of thrombotic events. Copyright (c) 2010 National Stroke Association. Published by Elsevier Inc. All rights reserved.
OBJECTIVE: We sought to clarify risk factor profiles and current treatment of Japanese patients with stroke, myocardial infarction (MI), and nonvalvular atrial fibrillation (NVAF) using the database of the Japan Thrombosis Registry for Atrial Fibrillation, Coronary, or Cerebrovascular Events (J-TRACE). METHODS: J-TRACE is a nationwide multicenter cooperative cohort of Japanese patients with MI, stroke, and NVAF. Baseline characteristics of 8087 Japanese patients (5804 male, average age 68.7 years) with history of stroke (n=3554), MI (n=2291), or NVAF (n=2242) were analyzed. RESULTS: History of stroke (14.7%) was more frequent than history of MI (2.6%) in patients with stroke, whereas history of stroke (6.6%) was less frequent than history of MI (7.6%) in patients with MI. In patients with NVAF, history of stroke (14.3%) was far more frequent than history of MI (3.4%). Hypertension was more frequent in stroke (74.4%) than MI (62.0%) or NVAF (57.7%), whereas hypercholesterolemia, diabetes mellitus, and cigarette smoking were more prevalent in patients with MI (56.1%, 35.1%, and 33.3%, respectively) than in those with stroke (35.7%, 22.4%, and 19.7%, respectively) or NVAF (26.9%, 17.2%, and 16.1%, respectively). Alcohol consumption (34.9%) and obesity (body mass index>25) (32.8%) were most common in patients with NVAF. In all patients, nonmedication rates were higher in patients with hypercholesterolemia (29.8%) or diabetes (36.9%) than in those with hypertension (9.5%). Warfarin was used in 58.9% of patients with low-risk and 75.4% with high-risk NVAF. CONCLUSION: Risk factor profiles and their modification were not similar among patients in Japan with MI, stroke, and NVAF, although they share a high risk of thrombotic events. Copyright (c) 2010 National Stroke Association. Published by Elsevier Inc. All rights reserved.
Authors: Chiao Wen Lim; Sazzli Kasim; Johan Rizwal Ismail; Nicholas Yul Chye Chua; Rizmy Najme Khir; Hafisyatul Aiza Zainal Abidin; Effarezan Abdul Rahman; Mohd Kamal Mohd Arshad; Zubin Ibrahim Othman; Khalid Yusoff Journal: Heart Asia Date: 2016-11-18
Authors: Jonathan C Hsu; Masaharu Akao; Mitsuru Abe; Karen L Anderson; Alvaro Avezum; Nathan Glusenkamp; Shun Kohsaka; Deirdre A Lane; Gregory Y H Lip; Chang-Sheng Ma; Frederick A Masoudi; Tatjana S Potpara; Teo Wee Siong; Mintu P Turakhia; Hung-Fat Tse; John S Rumsfeld; Thomas M Maddox Journal: J Am Heart Assoc Date: 2016-11-02 Impact factor: 5.501