| Literature DB >> 20433893 |
Fabienne Laugerette1, Cécile Vors, Noël Peretti, Marie-Caroline Michalski.
Abstract
Metabolic diseases such as obesity are characterized by a subclinical inflammatory state that contributes to the development of insulin resistance and atherosclerosis. Recent reports also indicate that (i) there are alterations of the intestinal microbiota in metabolic diseases and (ii) absorption of endogenous endotoxins (namely lipopolysaccharides, LPS) can occur, particularly during the digestion of lipids. The aim of the present review is to highlight recently gained knowledge regarding the links between high fat diets, lipid digestion, intestinal microbiota and metabolic endotoxemia & inflammation.Entities:
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Year: 2010 PMID: 20433893 DOI: 10.1016/j.biochi.2010.04.016
Source DB: PubMed Journal: Biochimie ISSN: 0300-9084 Impact factor: 4.079