| Literature DB >> 2043382 |
P Lichter1, A L Boyle, T Cremer, D C Ward.
Abstract
Nonisotopic in situ hybridization is a powerful tool to analyze the organization of complex genomes. Current approaches utilizing this technique for the analysis of linear and spatial genome organizations are presented. Clinical applications of these approaches, which open new avenues for diagnosis of disease-related chromosomal changes, are also discussed.Mesh:
Substances:
Year: 1991 PMID: 2043382 DOI: 10.1016/1050-3862(91)90005-c
Source DB: PubMed Journal: Genet Anal Tech Appl ISSN: 1050-3862