| Literature DB >> 20429598 |
Weijun Yao1, Lianjie Pan, Yihua Wu, Cheng Ma.
Abstract
A cinchona alkaloid-catalyzed domino Michael/hemiacetalization reaction of cyclic beta-oxo aldehydes and aromatic beta,gamma-unsaturated alpha-keto esters, resulting in the formation of spiro-dihydropyran architectures in good yield with high stereoselectivity (up to 97% ee), is presented.Entities:
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Year: 2010 PMID： 20429598 DOI： 10.1021/ol1007873
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005