Literature DB >> 20429084

Effect of age on the frequency of anxiety disorders in major depression with psychotic features.

Alastair J Flint1, Catherine Peasley-Miklus, Eros Papademetriou, Barnett S Meyers, Benoit H Mulsant, Anthony J Rothschild, Ellen M Whyte.   

Abstract

OBJECTIVE: To compare the frequency of anxiety disorders in older and younger persons with major depressive disorder with psychotic features.
DESIGN: Cross-sectional.
SETTING: University medical centers. PARTICIPANTS: Two hundred fifty-nine persons (N = 117 aged 18-59 years and N = 142 aged > or =60 years) with major depressive disorder with psychotic features who were enrolled in the Study of the Pharmacotherapy of Psychotic Depression (STOP-PD). MEASUREMENTS: Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, (DSM-IV) defined anxiety disorders were determined by Structured Clinical Interview for DSM-IV interview at baseline assessment. Younger and older participants were compared on the frequencies of any current anxiety disorder and any lifetime anxiety disorder, as well as the frequencies of individual anxiety disorders.
RESULTS: Older persons had significantly lower frequencies of any current anxiety disorder and any lifetime anxiety disorder, even after controlling for relevant demographic and clinical variables. With respect to specific anxiety disorders, older persons had significantly lower frequencies of current and lifetime panic disorder, current and lifetime social anxiety disorder, and current and lifetime posttraumatic stress disorder.
CONCLUSION: The findings of this study are consistent with those of community-based epidemiologic surveys that anxiety disorders are less prevalent in older than younger adults. Because of the rigorous assessment used in STOP-PD, our findings suggest that the age-related decline in the prevalence of anxiety disorders is not simply due to a failure to detect cases in older people, as has been previously suggested.

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Year:  2010        PMID: 20429084      PMCID: PMC3306059          DOI: 10.1097/jgp.0b013e3181c294ac

Source DB:  PubMed          Journal:  Am J Geriatr Psychiatry        ISSN: 1064-7481            Impact factor:   4.105


  34 in total

1.  A rating scale for depression.

Authors:  M HAMILTON
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2.  Anxiety and its disorders in late life: moving the field forward.

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3.  Rating chronic medical illness burden in geropsychiatric practice and research: application of the Cumulative Illness Rating Scale.

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Review 4.  Prevalence of anxiety disorders in elderly adults: a critical analysis.

Authors:  K Fuentes; B J Cox
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5.  Age differences in depression and anxiety symptoms: a structural equation modelling analysis of data from a general population sample.

Authors:  H Christensen; A F Jorm; A J Mackinnon; A E Korten; P A Jacomb; A S Henderson; B Rodgers
Journal:  Psychol Med       Date:  1999-03       Impact factor: 7.723

Review 6.  Epidemiology and comorbidity of anxiety disorders in later life: implications for treatment.

Authors:  A J Flint
Journal:  Clin Neurosci       Date:  1997

Review 7.  Do older Australians truly have low rates of anxiety and depression? A critique of the 1997 National Survey of Mental Health and Wellbeing.

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8.  Prevalence of anxiety disorders and their comorbidity with mood and addictive disorders.

Authors:  D A Regier; D S Rae; W E Narrow; C T Kaelber; A F Schatzberg
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9.  Anxiety disorders in later life: a report from the Longitudinal Aging Study Amsterdam.

Authors:  A T Beekman; M A Bremmer; D J Deeg; A J van Balkom; J H Smit; E de Beurs; R van Dyck; W van Tilburg
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Review 10.  Reliability of the Structured Clinical Interview for DSM-III-R: an evaluative review.

Authors:  D L Segal; M Hersen; V B Van Hasselt
Journal:  Compr Psychiatry       Date:  1994 Jul-Aug       Impact factor: 3.735

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1.  A gender analysis of the study of pharmacotherapy of psychotic depression (STOP-PD): gender and age as predictors of response and treatment-associated changes in body mass index and metabolic measures.

Authors:  Kristina M Deligiannidis; Anthony J Rothschild; Bruce A Barton; Aimee R Kroll-Desrosiers; Barnett S Meyers; Alastair J Flint; Ellen M Whyte; Benoit H Mulsant
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Review 6.  Heterogeneity and Polygenicity in Psychiatric Disorders: A Genome-Wide Perspective.

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7.  The AGE Effect on Protective Behaviors During the COVID-19 Outbreak: Sociodemographic, Perceptions and Psychological Accounts.

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