Literature DB >> 20428106

Integrase illuminated.

Peter Cherepanov1.   

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Year:  2010        PMID: 20428106      PMCID: PMC2868546          DOI: 10.1038/embor.2010.58

Source DB:  PubMed          Journal:  EMBO Rep        ISSN: 1469-221X            Impact factor:   8.807


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  7 in total

1.  Crystal structures of RNase H bound to an RNA/DNA hybrid: substrate specificity and metal-dependent catalysis.

Authors:  Marcin Nowotny; Sergei A Gaidamakov; Robert J Crouch; Wei Yang
Journal:  Cell       Date:  2005-07-01       Impact factor: 41.582

2.  Retroviral DNA integration: reaction pathway and critical intermediates.

Authors:  Min Li; Michiyo Mizuuchi; Terrence R Burke; Robert Craigie
Journal:  EMBO J       Date:  2006-02-16       Impact factor: 11.598

3.  Inhibitors of strand transfer that prevent integration and inhibit HIV-1 replication in cells.

Authors:  D J Hazuda; P Felock; M Witmer; A Wolfe; K Stillmock; J A Grobler; A Espeseth; L Gabryelski; W Schleif; C Blau; M D Miller
Journal:  Science       Date:  2000-01-28       Impact factor: 47.728

4.  Crystal structure of the catalytic domain of HIV-1 integrase: similarity to other polynucleotidyl transferases.

Authors:  F Dyda; A B Hickman; T M Jenkins; A Engelman; R Craigie; D R Davies
Journal:  Science       Date:  1994-12-23       Impact factor: 47.728

5.  HIV-1 integrase inhibitors that compete with the target DNA substrate define a unique strand transfer conformation for integrase.

Authors:  A S Espeseth; P Felock; A Wolfe; M Witmer; J Grobler; N Anthony; M Egbertson; J Y Melamed; S Young; T Hamill; J L Cole; D J Hazuda
Journal:  Proc Natl Acad Sci U S A       Date:  2000-10-10       Impact factor: 11.205

6.  Retroviral intasome assembly and inhibition of DNA strand transfer.

Authors:  Stephen Hare; Saumya Shree Gupta; Eugene Valkov; Alan Engelman; Peter Cherepanov
Journal:  Nature       Date:  2010-01-31       Impact factor: 49.962

7.  Subgroup and resistance analyses of raltegravir for resistant HIV-1 infection.

Authors:  David A Cooper; Roy T Steigbigel; Jose M Gatell; Jurgen K Rockstroh; Christine Katlama; Patrick Yeni; Adriano Lazzarin; Bonaventura Clotet; Princy N Kumar; Joseph E Eron; Mauro Schechter; Martin Markowitz; Mona R Loutfy; Jeffrey L Lennox; Jing Zhao; Joshua Chen; Desmond M Ryan; Rand R Rhodes; John A Killar; Lucinda R Gilde; Kim M Strohmaier; Anne R Meibohm; Michael D Miller; Daria J Hazuda; Michael L Nessly; Mark J DiNubile; Robin D Isaacs; Hedy Teppler; Bach-Yen Nguyen
Journal:  N Engl J Med       Date:  2008-07-24       Impact factor: 91.245

  7 in total
  12 in total

1.  Development of tricyclic hydroxy-1H-pyrrolopyridine-trione containing HIV-1 integrase inhibitors.

Authors:  Xue Zhi Zhao; Kasthuraiah Maddali; Mathieu Metifiot; Steven J Smith; B Christie Vu; Christophe Marchand; Stephen H Hughes; Yves Pommier; Terrence R Burke
Journal:  Bioorg Med Chem Lett       Date:  2011-03-21       Impact factor: 2.823

2.  Prospective strategies for targeting HIV-1 integrase function.

Authors:  Yang Luo; Mark A Muesing
Journal:  Future Med Chem       Date:  2010-07       Impact factor: 3.808

3.  HIV Drug Resistance and the Advent of Integrase Inhibitors.

Authors:  Peter K Quashie; Thibault Mesplède; Mark A Wainberg
Journal:  Curr Infect Dis Rep       Date:  2013-02       Impact factor: 3.725

4.  Sequential deletion of the integrase (Gag-Pol) carboxyl terminus reveals distinct phenotypic classes of defective HIV-1.

Authors:  Kevin D Mohammed; Michael B Topper; Mark A Muesing
Journal:  J Virol       Date:  2011-03-02       Impact factor: 5.103

5.  Dual and Opposite Effects of hRAD51 Chemical Modulation on HIV-1 Integration.

Authors:  Sylvain Thierry; Mohamed Salah Benleulmi; Ludivine Sinzelle; Eloise Thierry; Christina Calmels; Stephane Chaignepain; Pierre Waffo-Teguo; Jean-Michel Merillon; Brian Budke; Jean-Max Pasquet; Simon Litvak; Angela Ciuffi; Patrick Sung; Philip Connell; Ilona Hauber; Joachim Hauber; Marie-Line Andreola; Olivier Delelis; Vincent Parissi
Journal:  Chem Biol       Date:  2015-06-04

Review 6.  HIV-1 integrase multimerization as a therapeutic target.

Authors:  Lei Feng; Ross C Larue; Alison Slaughter; Jacques J Kessl; Mamuka Kvaratskhelia
Journal:  Curr Top Microbiol Immunol       Date:  2015       Impact factor: 4.291

7.  The Competitive Interplay between Allosteric HIV-1 Integrase Inhibitor BI/D and LEDGF/p75 during the Early Stage of HIV-1 Replication Adversely Affects Inhibitor Potency.

Authors:  Lei Feng; Venkatasubramanian Dharmarajan; Erik Serrao; Ashley Hoyte; Ross C Larue; Alison Slaughter; Amit Sharma; Matthew R Plumb; Jacques J Kessl; James R Fuchs; Frederic D Bushman; Alan N Engelman; Patrick R Griffin; Mamuka Kvaratskhelia
Journal:  ACS Chem Biol       Date:  2016-03-02       Impact factor: 5.100

8.  A New Class of Allosteric HIV-1 Integrase Inhibitors Identified by Crystallographic Fragment Screening of the Catalytic Core Domain.

Authors:  Disha Patel; Janet Antwi; Pratibha C Koneru; Erik Serrao; Stefano Forli; Jacques J Kessl; Lei Feng; Nanjie Deng; Ronald M Levy; James R Fuchs; Arthur J Olson; Alan N Engelman; Joseph D Bauman; Mamuka Kvaratskhelia; Eddy Arnold
Journal:  J Biol Chem       Date:  2016-09-19       Impact factor: 5.157

Review 9.  Foamy virus biology and its application for vector development.

Authors:  Dirk Lindemann; Axel Rethwilm
Journal:  Viruses       Date:  2011-05-11       Impact factor: 5.048

10.  Synthesis and Evaluation of Aryl Quinolines as HIV-1 Integrase Multimerization Inhibitors.

Authors:  Nicholas G Jentsch; Alison P Hart; Jared D Hume; Jian Sun; Kaitlin A McNeely; Chiyang Lama; Julie A Pigza; Matthew G Donahue; Jacques J Kessl
Journal:  ACS Med Chem Lett       Date:  2018-09-14       Impact factor: 4.632

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