| Literature DB >> 20426354 |
Abstract
Paracetamol and ibuprofen are safe and effective medications for reducing a fever in children and young people and they are often administered together with a view to reducing a temperature quickly. National Institute for Health and Clinical Excellence guidelines dictate that only one of these drugs should be given at a time because there is no evidence to suggest that simultaneous use is more effective. This article summarises a literature search of randomised controlled trials carried out to identify which, if either, of these drugs is faster at reducing a fever. In the studies examined, ibuprofen was found to be marginally more effective. However, the maximum dose of paracetamol was not administered. There is a need for more methodologically sound research that uses equivalent doses of both drugs.Entities:
Mesh:
Substances:
Year: 2010 PMID: 20426354 DOI: 10.7748/paed2010.04.22.3.22.c7638
Source DB: PubMed Journal: Paediatr Nurs ISSN: 0962-9513