Literature DB >> 20426354

Fever management: evaluating the use of ibuprofen and paracetamol.

Jodie Crook1.   

Abstract

Paracetamol and ibuprofen are safe and effective medications for reducing a fever in children and young people and they are often administered together with a view to reducing a temperature quickly. National Institute for Health and Clinical Excellence guidelines dictate that only one of these drugs should be given at a time because there is no evidence to suggest that simultaneous use is more effective. This article summarises a literature search of randomised controlled trials carried out to identify which, if either, of these drugs is faster at reducing a fever. In the studies examined, ibuprofen was found to be marginally more effective. However, the maximum dose of paracetamol was not administered. There is a need for more methodologically sound research that uses equivalent doses of both drugs.

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Year:  2010        PMID: 20426354     DOI: 10.7748/paed2010.04.22.3.22.c7638

Source DB:  PubMed          Journal:  Paediatr Nurs        ISSN: 0962-9513


  5 in total

1.  A new ibuprofen derivative inhibits platelet aggregation and ROS mediated platelet apoptosis.

Authors:  Kodagahalli S Rakesh; Swamy Jagadish; Ajjampura C Vinayaka; Mahadevappa Hemshekhar; Manoj Paul; Ram M Thushara; Mahalingam S Sundaram; Toreshettahally R Swaroop; Chakrabhavi D Mohan; Marilinganadoddi P Sadashiva; Kempaiah Kemparaju; Kesturu S Girish; Kanchugarakoppal S Rangappa
Journal:  PLoS One       Date:  2014-09-19       Impact factor: 3.240

2.  An investigation of the views and practices of Australian community pharmacists on pain and fever management and clinical guidelines.

Authors:  John Mishriky; Ieva Stupans; Vincent Chan
Journal:  Pharm Pract (Granada)       Date:  2019-06-11

Review 3.  Effects of acetaminophen and ibuprofen monotherapy in febrile children: a meta-analysis of randomized controlled trials.

Authors:  Ning Kuo; Nien-Yin Su; Sen-Kuang Hou; Yi-No Kang
Journal:  Arch Med Sci       Date:  2021-08-22       Impact factor: 3.707

4.  Randomized comparative trial of efficacy of paracetamol, ibuprofen and paracetamol-ibuprofen combination for treatment of febrile children.

Authors:  Falgun Indravadan Vyas; Devang Ashwinkumar Rana; Piyush M Patel; Varsha Jitendra Patel; Rekha H Bhavsar
Journal:  Perspect Clin Res       Date:  2014-01

5.  UV spectrophotometric simultaneous determination of paracetamol and ibuprofen in combined tablets by derivative and wavelet transforms.

Authors:  Vu Dang Hoang; Dong Thi Ha Ly; Nguyen Huu Tho; Hue Minh Thi Nguyen
Journal:  ScientificWorldJournal       Date:  2014-02-19
  5 in total

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