Literature DB >> 20425210

Pain and opioid addiction: what is the connection?

Adam J Carinci1, Jianren Mao.   

Abstract

Addiction to opioid analgesics is an important and yet underinvestigated clinical issue, which has substantial implications in opioid therapy for chronic pain management. Problematic opioid use, including compulsive opioid seeking and addiction, arises in some fraction of opioid-treated chronic pain patients. The connection between chronic pain and opioid addiction is a complex interplay between psychological, epidemiological, and neurobiological factors. Herein, we explore this critical relationship.

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Year:  2010        PMID: 20425210     DOI: 10.1007/s11916-009-0086-x

Source DB:  PubMed          Journal:  Curr Pain Headache Rep        ISSN: 1534-3081


  38 in total

Review 1.  Opioid-induced abnormal pain sensitivity: implications in clinical opioid therapy.

Authors:  Jianren Mao
Journal:  Pain       Date:  2002-12       Impact factor: 6.961

2.  Facilitation of conditioned fear extinction by d-cycloserine is mediated by mitogen-activated protein kinase and phosphatidylinositol 3-kinase cascades and requires de novo protein synthesis in basolateral nucleus of amygdala.

Authors:  Y L Yang; K T Lu
Journal:  Neuroscience       Date:  2005       Impact factor: 3.590

3.  Health care reform in the United States: radical surgery needed now more than ever.

Authors:  Laxmaiah Manchikanti
Journal:  Pain Physician       Date:  2008-01       Impact factor: 4.965

4.  The involvement of glial cells in the development of morphine tolerance.

Authors:  P Song; Z Q Zhao
Journal:  Neurosci Res       Date:  2001-03       Impact factor: 3.304

5.  Prevalence of abuse and dependency in chronic pain patients.

Authors:  N G Hoffmann; O Olofsson; B Salen; L Wickstrom
Journal:  Int J Addict       Date:  1995-06

6.  Yohimbine prevents morphine-induced changes of glial fibrillary acidic protein in brainstem and alpha2-adrenoceptor gene expression in hippocampus.

Authors:  Elba Alonso; Elisa Garrido; Carmen Díez-Fernández; Carmen Pérez-García; Gonzalo Herradón; Laura Ezquerra; Thomas F Deuel; Luis F Alguacil
Journal:  Neurosci Lett       Date:  2006-11-22       Impact factor: 3.046

7.  Clinical guidelines for the use of chronic opioid therapy in chronic noncancer pain.

Authors:  Roger Chou; Gilbert J Fanciullo; Perry G Fine; Jeremy A Adler; Jane C Ballantyne; Pamela Davies; Marilee I Donovan; David A Fishbain; Kathy M Foley; Jeffrey Fudin; Aaron M Gilson; Alexander Kelter; Alexander Mauskop; Patrick G O'Connor; Steven D Passik; Gavril W Pasternak; Russell K Portenoy; Ben A Rich; Richard G Roberts; Knox H Todd; Christine Miaskowski
Journal:  J Pain       Date:  2009-02       Impact factor: 5.820

8.  Expenditures and health status among adults with back and neck problems.

Authors:  Brook I Martin; Richard A Deyo; Sohail K Mirza; Judith A Turner; Bryan A Comstock; William Hollingworth; Sean D Sullivan
Journal:  JAMA       Date:  2008-02-13       Impact factor: 56.272

9.  Prescription opioid aberrant behaviors: a pilot study of sex differences.

Authors:  Sudie E Back; Rebecca A Payne; Angela E Waldrop; Arthur Smith; Scott Reeves; Kathleen T Brady
Journal:  Clin J Pain       Date:  2009 Jul-Aug       Impact factor: 3.442

Review 10.  Opioid-induced glial activation: mechanisms of activation and implications for opioid analgesia, dependence, and reward.

Authors:  Mark R Hutchinson; Sondra T Bland; Kirk W Johnson; Kenner C Rice; Steven F Maier; Linda R Watkins
Journal:  ScientificWorldJournal       Date:  2007-11-02
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  2 in total

Review 1.  The missing p in psychiatric training: why it is important to teach pain to psychiatrists.

Authors:  Igor Elman; Jon-Kar Zubieta; David Borsook
Journal:  Arch Gen Psychiatry       Date:  2011-01

Review 2.  Improving public health through access to and utilization of medication assisted treatment.

Authors:  Thomas F Kresina; Robert Lubran
Journal:  Int J Environ Res Public Health       Date:  2011-10-24       Impact factor: 3.390

  2 in total

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