BACKGROUND: We developed the Korean version of the Frontal Assessment Battery (FAB-K), evaluated its psychometric properties and constructed normative data for Korean elders. METHODS: FAB-K was administered to 300 Alzheimer's disease (AD) patients and 635 normal controls. Reliability of FAB-K was evaluated by testing its internal consistency, test-retest and inter-rater reliabilities. Validity of FAB-K was evaluated by testing discriminant validity for AD and concurrent validity with other frontal function tests. Age- and education-specific normative data of FAB-K were developed. RESULTS: Cronbach's alpha, inter-rater reliability and test-retest reliability of FAB-K were 0.802, 0.980 (p < 0.001) and 0.820 (p < 0.001), respectively. FAB-K exhibited significant correlations with the scores of MMSE and other frontal function tests (p < 0.01). Total and item scores of FAB-K were lower in AD patients than in controls and became worse as clinical dementia rating increased (F = 192.026, d.f. = 4, p < 0.001). The optimal cut-off score of FAB-K for AD was determined as 10/11, where sensitivity and specificity for AD were 0.717 and 0.827, respectively. Normative data were stratified by 3 age groups and 4 education groups. CONCLUSION: The FAB-K is a valid and reliable instrument for evaluating frontal dysfunction, and may be useful for screening AD. Copyright (c) 2010 S. Karger AG, Basel.
BACKGROUND: We developed the Korean version of the Frontal Assessment Battery (FAB-K), evaluated its psychometric properties and constructed normative data for Korean elders. METHODS:FAB-K was administered to 300 Alzheimer's disease (AD) patients and 635 normal controls. Reliability of FAB-K was evaluated by testing its internal consistency, test-retest and inter-rater reliabilities. Validity of FAB-K was evaluated by testing discriminant validity for AD and concurrent validity with other frontal function tests. Age- and education-specific normative data of FAB-K were developed. RESULTS: Cronbach's alpha, inter-rater reliability and test-retest reliability of FAB-K were 0.802, 0.980 (p < 0.001) and 0.820 (p < 0.001), respectively. FAB-K exhibited significant correlations with the scores of MMSE and other frontal function tests (p < 0.01). Total and item scores of FAB-K were lower in ADpatients than in controls and became worse as clinical dementia rating increased (F = 192.026, d.f. = 4, p < 0.001). The optimal cut-off score of FAB-K for AD was determined as 10/11, where sensitivity and specificity for AD were 0.717 and 0.827, respectively. Normative data were stratified by 3 age groups and 4 education groups. CONCLUSION: The FAB-K is a valid and reliable instrument for evaluating frontal dysfunction, and may be useful for screening AD. Copyright (c) 2010 S. Karger AG, Basel.
Authors: Jee Wook Kim; Dong Young Lee; Eun Hyun Seo; Bo Kyung Sohn; Shin Young Park; Il Han Choo; Jong Chul Youn; Jin Hyeong Jhoo; Ki Woong Kim; Jong Inn Woo Journal: J Korean Med Sci Date: 2013-09-25 Impact factor: 2.153