Literature DB >> 20421881

Are anti-C1q antibodies different from other SLE autoantibodies?

Matthew C Pickering1, Marina Botto.   

Abstract

Anti-C1q antibodies were first identified as low-molecular weight C1q precipitins in the sera of patients with systemic lupus erythematosus (SLE) over 30 years ago. Anti-C1q antibodies are strongly associated with the development of proliferative lupus nephritis, so much so that active renal inflammation in SLE patients is very unlikely if these antibodies are not present. These antibodies seem to develop through mechanisms that are similar to those of other SLE autoantibodies.

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Year:  2010        PMID: 20421881     DOI: 10.1038/nrrheum.2010.56

Source DB:  PubMed          Journal:  Nat Rev Rheumatol        ISSN: 1759-4790            Impact factor:   20.543


  29 in total

Review 1.  Systemic lupus erythematosus, complement deficiency, and apoptosis.

Authors:  M C Pickering; M Botto; P R Taylor; P J Lachmann; M J Walport
Journal:  Adv Immunol       Date:  2000       Impact factor: 3.543

Review 2.  Anti-C1q autoantibodies.

Authors:  Cees G M Kallenberg
Journal:  Autoimmun Rev       Date:  2008-07-09       Impact factor: 9.754

3.  High prevalence of anti-C1q antibodies in biopsy-proven active lupus nephritis.

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4.  Anti-C1q antibodies may help in diagnosing a renal flare in lupus nephritis.

Authors:  G Moroni; M Trendelenburg; N Del Papa; S Quaglini; E Raschi; P Panzeri; C Testoni; A Tincani; G Banfi; G Balestrieri; J A Schifferli; P L Meroni; C Ponticelli
Journal:  Am J Kidney Dis       Date:  2001-03       Impact factor: 8.860

5.  Autoantibodies against C1q in systemic lupus erythematosus are antigen-driven.

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Journal:  J Immunol       Date:  2009-12-15       Impact factor: 5.422

6.  Familial clustering of non-nuclear autoantibodies and C3 and C4 complement components in systemic lupus erythematosus.

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Journal:  Arthritis Rheum       Date:  2008-04

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Authors:  V Michael Holers
Journal:  J Clin Invest       Date:  2004-09       Impact factor: 14.808

8.  Anti-C1q autoantibodies deposit in glomeruli but are only pathogenic in combination with glomerular C1q-containing immune complexes.

Authors:  Leendert A Trouw; Tom W L Groeneveld; Marc A Seelen; Jacques M G J Duijs; Ingeborg M Bajema; Frans A Prins; Uday Kishore; David J Salant; J Sjef Verbeek; Cees van Kooten; Mohamed R Daha
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9.  IgG and IgA autoantibodies to C1q in systemic and renal diseases.

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  17 in total

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Journal:  Clin Rev Allergy Immunol       Date:  2011-06       Impact factor: 8.667

2.  Anti-C1q autoantibodies as markers of renal involvement in childhood-onset systemic lupus erythematosus.

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3.  Biomarkers in systemic lupus erythematosus: challenges and prospects for the future.

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4.  PTX3, Anti-PTX3, and Anti-C1q Autoantibodies in Lupus Glomerulonephritis.

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Review 5.  Role of the innate and adaptive immune responses in the pathogenesis of systemic lupus erythematosus.

Authors:  Nasim Bolouri; Maryam Akhtari; Elham Farhadi; Reza Mansouri; Seyedeh Tahereh Faezi; Ahmadreza Jamshidi; Mahdi Mahmoudi
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6.  Anti-C1q Antibody is Associated with Renal and Cutaneous Manifestations in Asian Indian Patients with Systemic Lupus Erythematosus.

Authors:  Jayakanthan Kabeerdoss; Nikhil Gupta; Sandhya Pulukool; Hindhumathi Mohan; Gowri Mahasampath; Debashish Danda
Journal:  J Clin Diagn Res       Date:  2017-03-01

7.  Functional Characterization of Autoantibodies against Complement Component C3 in Patients with Lupus Nephritis.

Authors:  Vasil V Vasilev; Remi Noe; Marie-Agnes Dragon-Durey; Sophie Chauvet; Valentin J Lazarov; Boriana P Deliyska; Veronique Fremeaux-Bacchi; Jordan D Dimitrov; Lubka T Roumenina
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Review 8.  Standardization of autoantibody testing: a paradigm for serology in rheumatic diseases.

Authors:  Pier Luigi Meroni; Martina Biggioggero; Silvia S Pierangeli; Joanna Sheldon; Ingrid Zegers; Maria Orietta Borghi
Journal:  Nat Rev Rheumatol       Date:  2013-11-26       Impact factor: 20.543

Review 9.  Mechanisms of Kidney Injury in Lupus Nephritis - the Role of Anti-dsDNA Antibodies.

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Journal:  Front Immunol       Date:  2015-09-15       Impact factor: 7.561

10.  Antibodies against C1q Are a Valuable Serological Marker for Identification of Systemic Lupus Erythematosus Patients with Active Lupus Nephritis.

Authors:  Shuhong Chi; Yunxia Yu; Juan Shi; Yurong Zhang; Jijuan Yang; Lijuan Yang; Xiaoming Liu
Journal:  Dis Markers       Date:  2015-10-13       Impact factor: 3.434

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