Literature DB >> 20418229

Subclinical thyroid disorders: significance and clinical impact.

Salman Razvi1, Jolanta U Weaver, Simon H S Pearce.   

Abstract

Subclinical thyroid diseases are defined by abnormal serum thyroid stimulating hormone (TSH) levels associated with normal thyroid hormone concentrations. The diagnosis of these conditions depends on defining the 'normal' euthyroid TSH range; in this review, arguments for and against lowering the upper limit of TSH are summarised. Although, subclinical hypothyroidism and subclinical hyperthyroidism are frequently encountered, their long-term consequences are debated due to conflicting results from many observational studies. The causes, effects and outcomes of treatment of both subclinical diseases are described, and the direction of future research in these conditions is outlined.

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Year:  2010        PMID： 20418229     DOI： 10.1136/jcp.2008.057414

Source DB:  PubMed          Journal:  J Clin Pathol        ISSN： 0021-9746            Impact factor:   3.411


  17 in total

1.  European thyroid association guidelines on L-t4 + L-t3 combination for hypothyroidism: a weary step in the right direction.

Authors:  Petros Perros
Journal:  Eur Thyroid J       Date:  2012-07

Review 2.  The TSH upper reference limit: where are we at?

Authors:  Peter Laurberg; Stig Andersen; Allan Carlé; Jesper Karmisholt; Nils Knudsen; Inge Bülow Pedersen
Journal:  Nat Rev Endocrinol       Date:  2011-02-08       Impact factor: 43.330

3.  Profiling retrospective thyroid function data in complete thyroidectomy patients to investigate the HPT axis set point (PREDICT-IT).

Authors:  E Li; P M Yen; J W Dietrich; M K-S Leow
Journal:  J Endocrinol Invest       Date:  2020-08-17       Impact factor: 4.256

4.  Subclinical thyroid dysfunction and functional capacity among elderly.

Authors:  Vanessa S Virgini; Liselotte W Wijsman; Nicolas Rodondi; Douglas C Bauer; Patricia M Kearney; Jacobijn Gussekloo; Wendy P J den Elzen; J Wouter Jukema; Rudi G J Westendorp; Ian Ford; David J Stott; Simon P Mooijaart
Journal:  Thyroid       Date:  2013-11-13       Impact factor: 6.568

5.  Subclinical Thyroid Dysfunction and Frailty Among Older Men.

Authors:  Vanessa S Virgini; Nicolas Rodondi; Peggy M Cawthon; Stephanie Litwack Harrison; Andrew R Hoffman; Eric S Orwoll; Kristine E Ensrud; Douglas C Bauer
Journal:  J Clin Endocrinol Metab       Date:  2015-10-23       Impact factor: 5.958

6.  Subclinical hypothyroidism is associated with increased risk for cancer mortality in adult Taiwanese-a 10 years population-based cohort.

Authors:  Fen-Yu Tseng; Wen-Yuan Lin; Chia-Ing Li; Tsai-Chung Li; Cheng-Chieh Lin; Kuo-Chin Huang
Journal:  PLoS One       Date:  2015-04-01       Impact factor: 3.240

7.  Subclinical hypothyroidism is an independent predictor of adverse cardiovascular outcomes in patients with acute decompensated heart failure.

Authors:  Tomohiro Hayashi; Takuya Hasegawa; Hideaki Kanzaki; Akira Funada; Makoto Amaki; Hiroyuki Takahama; Takahiro Ohara; Yasuo Sugano; Satoshi Yasuda; Hisao Ogawa; Toshihisa Anzai
Journal:  ESC Heart Fail       Date:  2016-03-24

8.  Diffuse Myocardial Injuries are Present in Subclinical Hypothyroidism: A Clinical Study Using Myocardial T1-mapping Quantification.

Authors:  Zhi Yao; Xia Gao; Min Liu; Zhe Chen; Ning Yang; Yu-Mei Jia; Xiao-Meng Feng; Yuan Xu; Xin-Chun Yang; Guang Wang
Journal:  Sci Rep       Date:  2018-03-22       Impact factor: 4.379

9.  Subclinical and overt hypothyroidism is associated with reduced glomerular filtration rate and proteinuria: a large cross-sectional population study.

Authors:  Yi-Cheng Chang; Chia Hsuin Chang; Yi-Chun Yeh; Lee-Ming Chuang; Yu-Kang Tu
Journal:  Sci Rep       Date:  2018-02-01       Impact factor: 4.379

10.  Age- and gender-specific reference intervals of TSH and free T4 in an iodine-replete area: Data from Korean National Health and Nutrition Examination Survey IV (2013-2015).

Authors:  So Young Park; Hae In Kim; Hyun-Kyung Oh; Tae Hyuk Kim; Hye Won Jang; Jae Hoon Chung; Myung-Hee Shin; Sun Wook Kim
Journal:  PLoS One       Date:  2018-02-01       Impact factor: 3.240
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