Literature DB >> 20418023

Radiation for Hodgkin's lymphoma in young female patients: a new technique to avoid the breasts and decrease the dose to the heart.

Bouthaina S Dabaja1, Neal C S Rebueno, Ali Mazloom, Scott Thorne, Kelly J Perrin, Naresh Tolani, Pragnan Das, Marc E Delclos, Puneeth Iyengar, Valerie K Reed, Patrecia Horace, Mohammad R Salehpour.   

Abstract

PURPOSE: To demonstrate how, in young female patients with Hodgkin's lymphoma, using an inclined board technique can further decrease the volume of breasts and heart in the treatment field. METHODS AND MATERIALS: An inclined board was constructed with the ability to mount an Aquaplast face mask, a Vacu-Lock, and a hip stopper. Eight female patients with early-stage Hodgkin's lymphoma were planned and compared using the conventional flat position and the inclined board position. All patients on the inclined board were planned with 90° degree table position and 15° gantry angle rotation to compensate for the beam divergence resulting from the patient's position on the inclined board. Dose-volume histograms were generated, as well as the mean V30 and V5 of both breasts and heart using both treatment positions.
RESULTS: The mean value of V30 of the right breast, left breast, and heart decreased from 3%, 3%, and 13%, respectively, using the flat position to 0, 0.4%, and 5%, respectively, using the inclined board. The mean value of V5 of the right breast, left breast, and heart decreased from 6%, 13%, and 36%, respectively, using the flat position to 2%, 8%, and 29%, respectively, using the inclined board.
CONCLUSIONS: Compared with conventional flat positioning, this simple device and technique allows better sparing of the breasts and the heart while maintaining comparable target coverage and total lung dose. Copyright Â
© 2011 Elsevier Inc. All rights reserved.

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Year:  2010        PMID: 20418023     DOI: 10.1016/j.ijrobp.2009.11.013

Source DB:  PubMed          Journal:  Int J Radiat Oncol Biol Phys        ISSN: 0360-3016            Impact factor:   7.038


  8 in total

1.  Treatment of Early-Stage Unfavorable Hodgkin Lymphoma: Efficacy and Toxicity of 4 Versus 6 Cycles of ABVD Chemotherapy With Radiation.

Authors:  Jillian R Gunther; Michelle A Fanale; Jay P Reddy; Mani Akhtari; Grace L Smith; Chelsea C Pinnix; Sarah A Milgrom; Zeinab Abou Yehia; Pamela K Allen; Eleanor M Osborne; Osama Mawlawi; Bouthaina S Dabaja
Journal:  Int J Radiat Oncol Biol Phys       Date:  2016-04-13       Impact factor: 7.038

2.  Predictors of Hypothyroidism in Hodgkin Lymphoma Survivors After Intensity Modulated Versus 3-Dimensional Radiation Therapy.

Authors:  Chelsea C Pinnix; Laura Cella; Therese Y Andraos; Zeina Ayoub; Sarah A Milgrom; Jillian Gunther; Sonali Thosani; Christine Wogan; Manuel Conson; Vittoria D'Avino; Yasuhiro Oki; Michelle Fanale; Hun J Lee; Sattva Neelapu; Luis Fayad; Frederick Hagemeister; M Alma Rodriguez; Loretta J Nastoupil; Yago Nieto; Wei Qiao; Roberto Pacelli; Bouthaina Dabaja
Journal:  Int J Radiat Oncol Biol Phys       Date:  2018-03-14       Impact factor: 7.038

3.  Effect of Deep Inspiration Breath Hold on Normal Tissue Sparing With Intensity Modulated Radiation Therapy Versus Proton Therapy for Mediastinal Lymphoma.

Authors:  Amy C Moreno; Jillian R Gunther; Sarah Milgrom; C David Fuller; Tyler Williamson; Amy Liu; Richard Wu; X Ronald Zhu; Bouthaina S Dabaja; Chelsea C Pinnix
Journal:  Adv Radiat Oncol       Date:  2020-08-25

4.  Second malignancies in patients with Hodgkin's Lymphoma: Half a century of experience.

Authors:  Bouthaina Shbib Dabaja; David Boyce-Fappiano; Wenli Dong; Ethan Damron; Penny Fang; Jill Gunther; Maria A Rodriguez; Paolo Strati; Raphael Steiner; Ranjit Nair; Hun Lee; Zeinab Abou Yehia; Ferial Shihadeh; Chelsea Pinnix; Andrea K Ng
Journal:  Clin Transl Radiat Oncol       Date:  2022-05-13

5.  Proton therapy for adults with mediastinal lymphomas: the International Lymphoma Radiation Oncology Group guidelines.

Authors:  Bouthaina Shbib Dabaja; Bradford S Hoppe; John P Plastaras; Wayne Newhauser; Katerina Rosolova; Stella Flampouri; Radhe Mohan; N George Mikhaeel; Youlia Kirova; Lena Specht; Joachim Yahalom
Journal:  Blood       Date:  2018-08-14       Impact factor: 22.113

6.  Incidence and predictors of Lhermitte's sign among patients receiving mediastinal radiation for lymphoma.

Authors:  Bassem Youssef; JoAnn Shank; Jay P Reddy; Chelsea C Pinnix; George Farha; Mani Akhtari; Pamela K Allen; Michelle A Fanale; John A Garcia; Patricia H Horace; Sarah Milgrom; Grace Li Smith; Yago Nieto; Isadora Arzu; He Wang; Nathan Fowler; Maria Alma Rodriguez; Bouthaina Dabaja
Journal:  Radiat Oncol       Date:  2015-09-25       Impact factor: 3.481

7.  Dosimetric advantages of a "butterfly" technique for intensity-modulated radiation therapy for young female patients with mediastinal Hodgkin's lymphoma.

Authors:  Khinh Ranh Voong; Kelli McSpadden; Chelsea C Pinnix; Ferial Shihadeh; Valerie Reed; Mohammad R Salehpour; Isidora Arzu; He Wang; David Hodgson; John Garcia; Michalis Aristophanous; Bouthaina S Dabaja
Journal:  Radiat Oncol       Date:  2014-04-15       Impact factor: 3.481

8.  Does the Incidence of Treatment-Related Toxicity Plateau After Radiation Therapy: The Long-Term Impact of Integral Dose in Hodgkin's Lymphoma Survivors.

Authors:  Adam L Holtzman; John M Stahl; Simeng Zhu; Christopher G Morris; Bradford S Hoppe; Jessica E Kirwan; Nancy P Mendenhall
Journal:  Adv Radiat Oncol       Date:  2019-07-23
  8 in total

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