Literature DB >> 20417110

Aesthetic and functional radical surgery in young patients with stage one or two tongue cancer: a preliminary report.

Bin Zhang1, Hong-Zhang Huang, Chao-Bin Pan, Jian-Hui Xu, Jian-Guang Wang, Wei-Liang Chen.   

Abstract

INTRODUCTION: The effect of an initial radical cure and the post-operative quality of life in young patients with stage one or two tongue cancer seems to be more important than in old patients. The aim of this study was to achieve both optimal surgical effectiveness and improved post-operative quality of life for young patients with stage one or two tongue cancer.
MATERIALS AND METHODS: 7 patients under 40 years of age with T(1)-T(2)N(0)M(0) squamous cell carcinoma of tongue underwent aesthetic and functional radical surgery in which reconstruction of the defect in the oral cavity and conservation of the main functional organs in neck with good scar aesthetics in the face and neck were performed. The outcomes were assessed clinically.
RESULTS: No tumour recurrence was found in the tongue, floor of mouth or neck at the end of follow-up (at least 37 months). The appearance of the tongue and oral function was retained; function in face, neck and shoulder was maintained; a satisfactory cosmetic appearance of the face and neck was achieved.
CONCLUSIONS: Aesthetic and functional radical surgery could ensure radical cure and unchanged, or improved post-operative, quality of life in young patients with stage one or two tongue cancer.
Copyright © 2010 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.

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Year:  2010        PMID: 20417110     DOI: 10.1016/j.jcms.2010.03.011

Source DB:  PubMed          Journal:  J Craniomaxillofac Surg        ISSN: 1010-5182            Impact factor:   2.078


  3 in total

1.  Long non-coding RNA CCAT1 is a prognostic biomarker for the progression of oral squamous cell carcinoma via miR-181a-mediated Wnt/β-catenin signaling pathway.

Authors:  Guang-Hui Li; Zhong-Hui Ma; Xi Wang
Journal:  Cell Cycle       Date:  2019-09-04       Impact factor: 4.534

2.  Determinants for further wishes for cosmetic and reconstructive interventions in 1652 patients with surgical treated carcinomas of the oral cavity.

Authors:  Henrik Holtmann; Simon Spalthoff; Nils-Claudius Gellrich; Jörg Handschel; Julian Lommen; Norbert R Kübler; Gertrud Krüskemper; Majeed Rana; Karoline Sander
Journal:  Maxillofac Plast Reconstr Surg       Date:  2017-09-05

3.  Repression of CRNDE enhances the anti-tumour activity of CD8 + T cells against oral squamous cell carcinoma through regulating miR-545-5p and TIM-3.

Authors:  Yilong Ai; Siyuan Wu; Hai Gao; Haigang Wei; Zhe Tang; Xia Li; Chen Zou
Journal:  J Cell Mol Med       Date:  2021-11-02       Impact factor: 5.310

  3 in total

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