Amitha Domalpally1, Sapna Gangaputra, Qian Peng, Ronald P Danis. 1. Fundus Photograph Reading Center, Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.
Abstract
BACKGROUND AND OBJECTIVE: To evaluate and compare the intra-session repeatability of retinal thickness measurements from the Topcon 3D OCT 1000 (Topcon Medical Systems; Paramus, NJ), a spectral-domain optical coherence tomography (SD-OCT) system, with the Stratus (Carl Zeiss Meditec, Inc., Dublin, CA), a time-domain OCT (TD-OCT) system, in eyes with retinal diseases. PATIENTS AND METHODS: Repeated scans with both SD-OCT and TD-OCT were taken. Thickness measurements from high-quality scans were used to assess repeatability and compare measurements between the two instruments. RESULTS: Paired scans from 127 eyes were evaluated, of which 63 pairs were of high quality. Coefficients of repeatability and variation for the central subfield were 20.1 μm (2.6%) with SD-OCT and 27.4 μm (4%) with TD-OCT (P = .38). The mean difference in central subfield thickness between the two instruments was 24.5 μm (standard deviation = 20.9). CONCLUSION: Repeatability of retinal thickness measurements with the Topcon 3D OCT 1000 is comparable to the Stratus. The measurements of the two machines differ significantly and cannot be used interchangeably. Copyright 2010, SLACK Incorporated.
BACKGROUND AND OBJECTIVE: To evaluate and compare the intra-session repeatability of retinal thickness measurements from the Topcon 3D OCT 1000 (Topcon Medical Systems; Paramus, NJ), a spectral-domain optical coherence tomography (SD-OCT) system, with the Stratus (Carl Zeiss Meditec, Inc., Dublin, CA), a time-domain OCT (TD-OCT) system, in eyes with retinal diseases. PATIENTS AND METHODS: Repeated scans with both SD-OCT and TD-OCT were taken. Thickness measurements from high-quality scans were used to assess repeatability and compare measurements between the two instruments. RESULTS: Paired scans from 127 eyes were evaluated, of which 63 pairs were of high quality. Coefficients of repeatability and variation for the central subfield were 20.1 μm (2.6%) with SD-OCT and 27.4 μm (4%) with TD-OCT (P = .38). The mean difference in central subfield thickness between the two instruments was 24.5 μm (standard deviation = 20.9). CONCLUSION: Repeatability of retinal thickness measurements with the Topcon 3D OCT 1000 is comparable to the Stratus. The measurements of the two machines differ significantly and cannot be used interchangeably. Copyright 2010, SLACK Incorporated.
Authors: Jeong W Pak; Ashwini Narkar; Sapna Gangaputra; Ronald Klein; Barbara Klein; Stacy Meuer; Yijun Huang; Ronald P Danis Journal: Invest Ophthalmol Vis Sci Date: 2013-07-02 Impact factor: 4.799
Authors: Amitha Domalpally; Michael M Altaweel; John H Kempen; Dawn Myers; Janet L Davis; C Stephen Foster; Paul Latkany; Sunil K Srivastava; Richard J Stawell; Janet T Holbrook Journal: Ocul Immunol Inflamm Date: 2012-11-19 Impact factor: 3.070
Authors: Susan B Bressler; Allison R Edwards; Kakarla V Chalam; Neil M Bressler; Adam R Glassman; Glenn J Jaffe; Michele Melia; David D Saggau; Oren Z Plous Journal: JAMA Ophthalmol Date: 2014-09 Impact factor: 7.389