BACKGROUND: In twin births, both babies have the same gestational age and pre-natal conditions. However, twins may develop a varied retinopathy of prematurity (ROP) course depending on birth weight and other systemic factors. OBJECTIVE: To study the profile of asymmetric ROP in twins DESIGN: Retrospective study. SETTING: Tertiary ROP referral eye hospital. MATERIALS AND METHODS: The profile of 56 pairs of twins with ROP were studied and analyzed for differences in zone or need for treatment, while studying possible causes for the varied outcome. RESULTS: In 45 pairs of twins (80%) the disease progressed identically in both eyes, while in 11 pairs (20%) the ROP showed differences in zone or need for treatment. Four of these pairs were discordant. In 3 of these 4 pairs, the heavier birth weight twin had a more severe ROP course. CONCLUSIONS: Twins can present with asymmetric ROP course, and it is therefore essential to examine both twins as per screening protocols.
BACKGROUND: In twin births, both babies have the same gestational age and pre-natal conditions. However, twins may develop a varied retinopathy of prematurity (ROP) course depending on birth weight and other systemic factors. OBJECTIVE: To study the profile of asymmetric ROP in twins DESIGN: Retrospective study. SETTING: Tertiary ROP referral eye hospital. MATERIALS AND METHODS: The profile of 56 pairs of twins with ROP were studied and analyzed for differences in zone or need for treatment, while studying possible causes for the varied outcome. RESULTS: In 45 pairs of twins (80%) the disease progressed identically in both eyes, while in 11 pairs (20%) the ROP showed differences in zone or need for treatment. Four of these pairs were discordant. In 3 of these 4 pairs, the heavier birth weight twin had a more severe ROP course. CONCLUSIONS: Twins can present with asymmetric ROP course, and it is therefore essential to examine both twins as per screening protocols.
Authors: J M Ortega-Molina; R Anaya-Alaminos; J Uberos-Fernández; A Solans-Pérez de Larraya; M J Chaves-Samaniego; A Salgado-Miranda; R Piñar-Molina; A Jerez-Calero; J L García-Serrano Journal: Mediators Inflamm Date: 2015-05-21 Impact factor: 4.711
Authors: Gordon S K Yau; Jacky W Y Lee; Victor T Y Tam; Stan Yip; Edith Cheng; Catherine C L Liu; Benjamin C Y Chu; Can Y F Yuen Journal: ScientificWorldJournal Date: 2014-10-23