| Literature DB >> 20413616 |
Abstract
Subclinical hypothyroidism (SH) is defined as an elevated thyroid stimulating hormone (TSH) in association with a normal total or free thyroxine (T4) or triiodothyronine (T3). It is frequently encountered in both neonatology and general paediatric practice; however, its clinical significance is widely debated. Currently there is no broad consensus on the investigation and treatment of these patients; specifically who to treat and what cut-off level of TSH should be used. This paper reviews the available evidence regarding investigation, treatments and outcomes reported for childhood SH.Entities:
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Year: 2010 PMID: 20413616 DOI: 10.1136/adc.2009.181800
Source DB: PubMed Journal: Arch Dis Child ISSN: 0003-9888 Impact factor: 3.791