Literature DB >> 20413333

Improved time-zero biomechanical properties using poly-L-lactic acid graft augmentation in a cadaveric rotator cuff repair model.

Jesse A McCarron1, Ryan A Milks, Xi Chen, Joseph P Iannotti, Kathleen A Derwin.   

Abstract

HYPOTHESIS: Rotator cuff repair failure rates range from 20% to 90%, and failure is believed to occur most commonly by sutures cutting through the tendon due to excessive tension at the repair site. This study was designed to determine whether application of a woven poly-L-lactic acid device (X-Repair; Synthasome, San Diego, CA) would improve the mechanical properties of rotator cuff repair in vitro.
MATERIALS AND METHODS: Eight pairs of human cadaveric shoulders were used to test augmented and non-augmented rotator cuff repairs. Initial stiffness, yield load, ultimate load, and failure mode were compared.
RESULTS: Yield load was 56% to 92% higher and ultimate load was 56% to 76% higher in augmented repairs. No increase in initial stiffness was found. Failure by sutures cutting through the tendon was reduced, occurring in 17 of 20 non-augmented repairs but only 7 of 20 augmented repairs.
CONCLUSIONS: Our data show that application of the X-Repair device significantly increased the yield load and ultimate load of rotator cuff repairs in a human cadaveric model and altered the failure mode but did not affect initial repair stiffness. 2010 Journal of Shoulder and Elbow Surgery Board of Trustees. Published by Mosby, Inc. All rights reserved.

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Year:  2010        PMID: 20413333     DOI: 10.1016/j.jse.2009.12.008

Source DB:  PubMed          Journal:  J Shoulder Elbow Surg        ISSN: 1058-2746            Impact factor:   3.019


  14 in total

Review 1.  Rotator cuff: biology and current arthroscopic techniques.

Authors:  Olaf Lorbach; Marc Tompkins
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2012-01-21       Impact factor: 4.342

Review 2.  [Patch augmentation of the rotator cuff. A reasonable choice or a waste of money?].

Authors:  M Flury
Journal:  Orthopade       Date:  2016-02       Impact factor: 1.087

3.  Braided and Stacked Electrospun Nanofibrous Scaffolds for Tendon and Ligament Tissue Engineering.

Authors:  Benjamin B Rothrauff; Brian B Lauro; Guang Yang; Richard E Debski; Volker Musahl; Rocky S Tuan
Journal:  Tissue Eng Part A       Date:  2017-02-10       Impact factor: 3.845

4.  The Rotator Cuff Organ: Integrating Developmental Biology, Tissue Engineering, and Surgical Considerations to Treat Chronic Massive Rotator Cuff Tears.

Authors:  Benjamin B Rothrauff; Thierry Pauyo; Richard E Debski; Mark W Rodosky; Rocky S Tuan; Volker Musahl
Journal:  Tissue Eng Part B Rev       Date:  2017-02-09       Impact factor: 6.389

5.  Functionally Graded, Bone- and Tendon-Like Polyurethane for Rotator Cuff Repair.

Authors:  Dai Fei Elmer Ker; Dan Wang; Anthony William Behn; Evelyna Tsi Hsin Wang; Xu Zhang; Benjamin Yamin Zhou; Ángel Enrique Mercado-Pagán; Sungwoo Kim; John Kleimeyer; Burhan Gharaibeh; Yaser Shanjani; Drew Nelson; Marc Safran; Emilie Cheung; Phil Campbell; Yunzhi Peter Yang
Journal:  Adv Funct Mater       Date:  2018-03-30       Impact factor: 18.808

6.  Does augmentation with a reinforced fascia patch improve rotator cuff repair outcomes?

Authors:  Andrew R Baker; Jesse A McCarron; Carmela D Tan; Joseph P Iannotti; Kathleen A Derwin
Journal:  Clin Orthop Relat Res       Date:  2012-09       Impact factor: 4.176

Review 7.  Scaffolds for tendon and ligament repair and regeneration.

Authors:  Anthony Ratcliffe; David L Butler; Nathaniel A Dyment; Paul J Cagle; Christopher S Proctor; Seena S Ratcliffe; Evan L Flatow
Journal:  Ann Biomed Eng       Date:  2015-02-04       Impact factor: 3.934

8.  The Role of Nanomaterials and Biological Agents on Rotator Cuff Regeneration.

Authors:  Kenyatta S Washington; Nikoo Saveh Shemshaki; Cato T Laurencin
Journal:  Regen Eng Transl Med       Date:  2020-09-23

9.  [Arthroscopic rotator cuff repair with patch augmentation].

Authors:  M Flury
Journal:  Oper Orthop Traumatol       Date:  2012-11       Impact factor: 1.154

10.  Scaffolds in tendon tissue engineering.

Authors:  Umile Giuseppe Longo; Alfredo Lamberti; Stefano Petrillo; Nicola Maffulli; Vincenzo Denaro
Journal:  Stem Cells Int       Date:  2011-12-11       Impact factor: 5.443

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