Literature DB >> 20413177

Patterns in the use of benzodiazepines in British Columbia: examining the impact of increasing research and guideline cautions against long-term use.

Colleen M Cunningham1, Gillian E Hanley, Steve Morgan.   

Abstract

OBJECTIVE: We examined changes in patterns of benzodiazepine use in British Columbia over a period of increasing evidence of harms associated with long-term use.
METHODS: Using linked administrative databases for the years 1996 and 2006, we performed logistic regression to examine how socio-economic and health factors affect the likelihood of benzodiazepine use and long-term use, and to test for changes in rates of use and long-term use over time.
RESULTS: In 2006, 8.4% of British Columbians used benzodiazepines, 3.5% long-term. Use was positively related with being female, lower income, older, and of poorer health status. Long-term use was positively associated with being in the lowest income quintile, of poorest health, and over the age of 65. While the rate of long-term use decreased from 1996 to 2006 for those over age 70, it increased in middle-aged populations.
CONCLUSIONS: Our results suggest, despite increased awareness of and cautions regarding risks associated with long-term use of benzodiazepines, rates of potentially inappropriate use have changed very little over a decade. Given that early use of benzodiazepines is positively associated with later long-term use, policies targeting populations younger than conventionally studied (i.e. those under age 65) may be needed to decrease rates of long-term use. Copyright (c) 2010 Elsevier Ireland Ltd. All rights reserved.

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Year:  2010        PMID: 20413177     DOI: 10.1016/j.healthpol.2010.03.008

Source DB:  PubMed          Journal:  Health Policy        ISSN: 0168-8510            Impact factor:   2.980


  32 in total

1.  Use of benzodiazepines and z-drugs not compliant with guidelines and associated factors: a population-based study.

Authors:  Arnaud Panes; Antoine Pariente; Anne Bénard-Laribière; Régis Lassalle; Caroline Dureau-Pournin; Simon Lorrain; Marie Tournier; Annie Fourrier-Réglat
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  2018-12-11       Impact factor: 5.270

Review 2.  Benzodiazepine Use, Misuse, and Harm at the Population Level in Canada: A Comprehensive Narrative Review of Data and Developments Since 1995.

Authors:  Yoko Murphy; Emily Wilson; Elliot M Goldner; Benedikt Fischer
Journal:  Clin Drug Investig       Date:  2016-07       Impact factor: 2.859

3.  Long-term sedative use among community-dwelling adults: a population-based analysis.

Authors:  Deirdre Weymann; Emilie J Gladstone; Kate Smolina; Steven G Morgan
Journal:  CMAJ Open       Date:  2017-03-03

4.  National Trends in Antidepressant, Benzodiazepine, and Other Sedative-Hypnotic Treatment of Older Adults in Psychiatric and Primary Care.

Authors:  Donovan T Maust; Frederic C Blow; Ilse R Wiechers; Helen C Kales; Steven C Marcus
Journal:  J Clin Psychiatry       Date:  2017-04       Impact factor: 4.384

5.  Benzodiazepines, Codispensed Opioids, and Mortality among Patients Initiating Long-Term In-Center Hemodialysis.

Authors:  Abimereki D Muzaale; Matthew Daubresse; Sunjae Bae; Nadia M Chu; Krista L Lentine; Dorry L Segev; Mara McAdams-DeMarco
Journal:  Clin J Am Soc Nephrol       Date:  2020-05-26       Impact factor: 8.237

6.  Benzodiazepines are Prescribed More Frequently to Patients Already at Risk for Benzodiazepine-Related Adverse Events in Primary Care.

Authors:  David S Kroll; Harry Reyes Nieva; Arthur J Barsky; Jeffrey A Linder
Journal:  J Gen Intern Med       Date:  2016-05-13       Impact factor: 5.128

7.  Increasing availability of benzodiazepines among people who inject drugs in a Canadian setting.

Authors:  Geoffrey Walton; Huiru Dong; M J Milloy; Kora DeBeck; Thomas Kerr; Evan Wood; Kanna Hayashi
Journal:  Subst Abus       Date:  2017-09-18       Impact factor: 3.716

8.  Patterns, predictors and persistence of chronic sedative use: a population-based observational study of older adults in British Columbia, Canada.

Authors:  Steven G Morgan; Deirdre Weymann
Journal:  Eur J Clin Pharmacol       Date:  2017-04-24       Impact factor: 2.953

9.  Use of benzodiazepines and related drugs in Manitoba: a population-based study.

Authors:  Silvia Alessi-Severini; James M Bolton; Murray W Enns; Matthew Dahl; David M Collins; Dan Chateau; Jitender Sareen
Journal:  CMAJ Open       Date:  2014-10-01

10.  Predicting chronic benzodiazepine use in adults with depressive disorder: Retrospective cohort study using administrative data in Quebec.

Authors:  Jean-Daniel Carrier; Pasquale Roberge; Josiane Courteau; Alain Vanasse
Journal:  Can Fam Physician       Date:  2016-08       Impact factor: 3.275

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