| Literature DB >> 20413135 |
G K Schwalfenberg1, S J Genuis, M N Hiltz.
Abstract
There is disturbing evidence of widespread vitamin D deficiency in many population groups, particularly within nations at high latitude. Numerous recent studies in the scientific literature associate vitamin D deficiency with a colossal increase in morbidity and mortality. Since Canada is at higher latitude, this review assesses the vitamin D status within the Canadian population. This review was prepared by assessing available medical and scientific literature from Medline, as well as by reviewing several books and conference proceedings. A standard 25(OH)D level of 75-80nmol/l or more was used to indicate vitamin D sufficiency. Between 70% and 97% of Canadians demonstrate vitamin D insufficiency. Furthermore, studies assessing 25(OH)D levels of vitamin D at 25-40nmol/l reveal that many Canadians have profoundly deficient levels. Repletion of vitamin D3 with 2000IU/day for those not receiving judicious sun exposure and those with no contra-indications would likely achieve normalized levels in more than 93% of patients, without risk of toxicity. Explicit directives regarding vitamin D assessment and management are urgently required. Copyright 2010 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved.Entities:
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Year: 2010 PMID: 20413135 DOI: 10.1016/j.puhe.2010.03.003
Source DB: PubMed Journal: Public Health ISSN: 0033-3506 Impact factor: 2.427