Literature DB >> 20412765

Realizing the promise of RNAi high throughput screening.

Chris Bakal1, Norbert Perrimon.   

Abstract

Recently reporting in Nature, Collinet et al. describes the application of quantitative multiparametric methods to a genome-wide RNAi screen for regulators of endocytosis. The study illustrates the power of this approach beyond the identification of new endocytic components to providing insights into the design principles of the endocytic system. Copyright 2010 Elsevier Inc. All rights reserved.

Entities:  

Year:  2010        PMID: 20412765      PMCID: PMC2868582          DOI: 10.1016/j.devcel.2010.04.005

Source DB:  PubMed          Journal:  Dev Cell        ISSN: 1534-5807            Impact factor:   12.270


  9 in total

1.  Gene clustering based on RNAi phenotypes of ovary-enriched genes in C. elegans.

Authors:  Fabio Piano; Aaron J Schetter; Diane G Morton; Kristin C Gunsalus; Valerie Reinke; Stuart K Kim; Kenneth J Kemphues
Journal:  Curr Biol       Date:  2002-11-19       Impact factor: 10.834

Review 2.  The endocytic matrix.

Authors:  Giorgio Scita; Pier Paolo Di Fiore
Journal:  Nature       Date:  2010-01-28       Impact factor: 49.962

Review 3.  Drosophila genome-wide RNAi screens: are they delivering the promise?

Authors:  B Mathey-Prevot; N Perrimon
Journal:  Cold Spring Harb Symp Quant Biol       Date:  2006

4.  Quantitative morphological signatures define local signaling networks regulating cell morphology.

Authors:  Chris Bakal; John Aach; George Church; Norbert Perrimon
Journal:  Science       Date:  2007-06-22       Impact factor: 47.728

5.  Full-genome RNAi profiling of early embryogenesis in Caenorhabditis elegans.

Authors:  B Sönnichsen; L B Koski; A Walsh; P Marschall; B Neumann; M Brehm; A-M Alleaume; J Artelt; P Bettencourt; E Cassin; M Hewitson; C Holz; M Khan; S Lazik; C Martin; B Nitzsche; M Ruer; J Stamford; M Winzi; R Heinkel; M Röder; J Finell; H Häntsch; S J M Jones; M Jones; F Piano; K C Gunsalus; K Oegema; P Gönczy; A Coulson; A A Hyman; C J Echeverri
Journal:  Nature       Date:  2005-03-24       Impact factor: 49.962

6.  Predictive models of molecular machines involved in Caenorhabditis elegans early embryogenesis.

Authors:  Kristin C Gunsalus; Hui Ge; Aaron J Schetter; Debra S Goldberg; Jing-Dong J Han; Tong Hao; Gabriel F Berriz; Nicolas Bertin; Jerry Huang; Ling-Shiang Chuang; Ning Li; Ramamurthy Mani; Anthony A Hyman; Birte Sönnichsen; Christophe J Echeverri; Frederick P Roth; Marc Vidal; Fabio Piano
Journal:  Nature       Date:  2005-08-11       Impact factor: 49.962

7.  Systems survey of endocytosis by multiparametric image analysis.

Authors:  Claudio Collinet; Martin Stöter; Charles R Bradshaw; Nikolay Samusik; Jochen C Rink; Denise Kenski; Bianca Habermann; Frank Buchholz; Robert Henschel; Matthias S Mueller; Wolfgang E Nagel; Eugenio Fava; Yannis Kalaidzidis; Marino Zerial
Journal:  Nature       Date:  2010-02-28       Impact factor: 49.962

Review 8.  Endocytosis and signalling: intertwining molecular networks.

Authors:  Alexander Sorkin; Mark von Zastrow
Journal:  Nat Rev Mol Cell Biol       Date:  2009-09       Impact factor: 94.444

9.  Phosphorylation networks regulating JNK activity in diverse genetic backgrounds.

Authors:  Chris Bakal; Rune Linding; Flora Llense; Elleard Heffern; Enrique Martin-Blanco; Tony Pawson; Norbert Perrimon
Journal:  Science       Date:  2008-10-17       Impact factor: 47.728

  9 in total
  3 in total

Review 1.  Systems biology approaches to new vaccine development.

Authors:  Ann L Oberg; Richard B Kennedy; Peter Li; Inna G Ovsyannikova; Gregory A Poland
Journal:  Curr Opin Immunol       Date:  2011-05-11       Impact factor: 7.486

2.  The transcriptional diversity of 25 Drosophila cell lines.

Authors:  Lucy Cherbas; Aarron Willingham; Dayu Zhang; Li Yang; Yi Zou; Brian D Eads; Joseph W Carlson; Jane M Landolin; Philipp Kapranov; Jacqueline Dumais; Anastasia Samsonova; Jeong-Hyeon Choi; Johnny Roberts; Carrie A Davis; Haixu Tang; Marijke J van Baren; Srinka Ghosh; Alexander Dobin; Kim Bell; Wei Lin; Laura Langton; Michael O Duff; Aaron E Tenney; Chris Zaleski; Michael R Brent; Roger A Hoskins; Thomas C Kaufman; Justen Andrews; Brenton R Graveley; Norbert Perrimon; Susan E Celniker; Thomas R Gingeras; Peter Cherbas
Journal:  Genome Res       Date:  2010-12-22       Impact factor: 9.043

3.  A direct look at RNAi screens.

Authors:  Alexis R Barr; Chris Bakal
Journal:  Mol Syst Biol       Date:  2012-04-24       Impact factor: 11.429

  3 in total

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