Literature DB >> 20411928

Cytotoxic nor-chamigrane and chamigrane endoperoxides from a basidiomycetous fungus.

Supichar Chokpaiboon1, Damrong Sommit, Thapong Teerawatananond, Nongnuj Muangsin, Taridaporn Bunyapaiboonsri, Khanitha Pudhom.   

Abstract

A new nor-chamigrane endoperoxide, merulin A (1), and two new chamigrane endoperoxides, merulins B and C (2, 3), were isolated from the culture broth extract of an endophytic fungus of Xylocarpus granatum. Their structures were elucidated on the basis of spectroscopic, mainly NMR and MS, data. X-ray crystallographic analysis confirmed the structure of 1. Compounds 1 and 3 displayed significant cytotoxicity against human breast (BT474) and colon (SW620) cancer cell lines.

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Year:  2010        PMID： 20411928     DOI： 10.1021/np100103j

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  8 in total

1.  Structure and absolute configuration assignments of ochracines F-L, chamigrane and cadinane sesquiterpenes from the basidiomycete Steccherinum ochraceum HFG119.

Authors:  Zhen-Zhu Zhao; Qi-Lu Zhao; Wei-Sheng Feng; Hai-Rong He; Meng Li; Gui-Min Xue; He-Ping Chen; Ji-Kai Liu
Journal:  RSC Adv       Date:  2021-05-24       Impact factor: 4.036

2.  Hit-to-lead development of the chamigrane endoperoxide merulin A for the treatment of African sleeping sickness.

Authors:  Gabriel Navarro; Supchar Chokpaiboon; Geraldine De Muylder; Walter M Bray; Sean C Nisam; James H McKerrow; Khanitha Pudhom; Roger G Linington
Journal:  PLoS One       Date:  2012-09-27       Impact factor: 3.240

3.  Molecular Phylogenetics and Biological Potential of Fungal Endophytes From Plants of the Sundarbans Mangrove.

Authors:  Md Sohanur Rahaman; Md Afjalus Siraj; Sabiha Sultana; Veronique Seidel; Md Amirul Islam
Journal:  Front Microbiol       Date:  2020-11-13       Impact factor: 5.640

Review 4.  Antiprotozoal and Antitumor Activity of Natural Polycyclic Endoperoxides: Origin, Structures and Biological Activity.

Authors:  Valery M Dembitsky; Ekaterina Ermolenko; Nick Savidov; Tatyana A Gloriozova; Vladimir V Poroikov
Journal:  Molecules       Date:  2021-01-28       Impact factor: 4.411

Review 5.  Putative Anticancer Compounds from Plant-Derived Endophytic Fungi: A Review.

Authors:  Md Hridoy; Md Zobayer Hossain Gorapi; Sadia Noor; Nargis Sultana Chowdhury; Md Mustafizur Rahman; Isabella Muscari; Francesco Masia; Sabrina Adorisio; Domenico V Delfino; Md Abdul Mazid
Journal:  Molecules       Date:  2022-01-04       Impact factor: 4.411

6.  Spirobisnaphthalenes from the mangrove-derived fungus Rhytidhysteron sp. AS21B.

Authors:  Khanitha Pudhom; Thapong Teerawatananond; Supichar Chookpaiboon
Journal:  Mar Drugs       Date:  2014-03-06       Impact factor: 5.118

7.  Chamigrane Sesquiterpenes from a Basidiomycetous Endophytic Fungus XG8D Associated with Thai Mangrove Xylocarpus granatum.

Authors:  Siwattra Choodej; Thapong Teerawatananond; Tohru Mitsunaga; Khanitha Pudhom
Journal:  Mar Drugs       Date:  2016-07-15       Impact factor: 5.118

Review 8.  Endophytic Fungi-Alternative Sources of Cytotoxic Compounds: A Review.

Authors:  Fazilath Uzma; Chakrabhavi D Mohan; Abeer Hashem; Narasimha M Konappa; Shobith Rangappa; Praveen V Kamath; Bhim P Singh; Venkataramana Mudili; Vijai K Gupta; Chandra N Siddaiah; Srinivas Chowdappa; Abdulaziz A Alqarawi; Elsayed F Abd Allah
Journal:  Front Pharmacol       Date:  2018-04-26       Impact factor: 5.810
  8 in total

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