Spontaneous regression in two unusual cases of advanced Coats' disease.

The authors present two cases of advanced Coats' disease having total exudative retinal detachment, in which the disease regressed spontaneously. The patients were a 4-year-old girl and 3-year-old boy with total retinal detachment with widespread vascular anomalies. In the follow-up, fundus examination revealed spontaneous regression. At this stage, photocoagulation and cryotherapy were applied. In case 1, the eye was stable during 2 months but recurrence started thereafter, which ended with phthisis. In case 2, the retina was still attached 6 months following surgery. The authors emphasize the possibility of spontaneous regression, even in advanced Coats' disease. Copyright 2010, SLACK Incorporated.