Literature DB >> 20411475

["STUMP" (smooth muscle tumour of uncertain malignant potential), a tumour of the uterus in pregnancy--a diagnostic and therapeutic challenge].

S Clauss1, S Höller, L Hegi, R Blum, I Hösli.   

Abstract

We present the case of a preterm birth in the 27 (th) week of gestation, probably due to a chorionamnionitis, with the coincidental finding of a STUMP (smooth muscle tumour of uncertain malignant potential). The STUMP is a rare tumour entity characterised by smooth muscle cells which is difficult to classify by means of histology. The WHO classification of mesenchymal tumours allocates STUMP as an intermediate tumour between a benign leiomyoma and a malignant leiomyosarcoma. If histological criteria of malignancy are not fulfilled because the type of necrosis is in doubt or the interpretation of mitotic figures is ambiguous and the tumour cannot reliably be classified as a leiomyoma, it is classified as a STUMP. Compared to malignant leiomyosarcoma, STUMP has a superior prognosis, but the biological potential of the tumour remains unclear; lymphogenic and haematogenic dissemination seems possible even after a long period of time. STUMP represents a challenge in diagnosis and treatment recommendations. We present the first description of a case of STUMP during pregnancy, raising the question of whether the histological finding in tumours of the uterus during pregnancy are important.

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Year:  2010        PMID: 20411475     DOI: 10.1055/s-0030-1249675

Source DB:  PubMed          Journal:  Z Geburtshilfe Neonatol        ISSN: 0948-2393            Impact factor:   0.685


  3 in total

1.  Acute abdomen with a parasitic smooth muscle tumor of uncertain malignant potential (STUMP) in pregnancy; a unique case report.

Authors:  Hannah Louise Price; Tanne Daniels; Tava Mudzamiri; Archana Pandita; Victoria Carlsen
Journal:  Int J Surg Case Rep       Date:  2022-10-13

2.  Clinical and reproductive outcomes of uterine smooth muscle tumor of uncertain malignant potential: a single-center retrospective study.

Authors:  Chengcheng Ning; Lihong Zhang; Chenyan Zhao; Xiaojun Chen; Xiaoxia Liu; Chao Gu
Journal:  J Int Med Res       Date:  2021-04       Impact factor: 1.671

3.  Successful pregnancy following myomectomy for uterine smooth muscle tumor of uncertain malignant potential: A case report and review of the literature.

Authors:  Jessica E Campbell; Jennifer F Knudtson; Philip T Valente; Randal D Robinson; Edward R Kost
Journal:  Gynecol Oncol Rep       Date:  2015-08-07
  3 in total

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