Literature DB >> 2041055

Increases in transforming growth factor-beta mRNA in hippocampus during response to entorhinal cortex lesions in intact and adrenalectomized rats.

N R Nichols1, N J Laping, J R Day, C E Finch.   

Abstract

Transforming growth factor-beta mRNA was detected with a rat TGF-beta 1 coding sequence probe as a 2.5 kb band by RNA blot hybridization of total RNA from the adult male rat hippocampus. Following electrolytic lesions of the entorhinal cortex that cause hippocampal deafferentation and synaptic remodeling, TGF-beta mRNA increases 5-fold in ipsilateral hippocampus when compared with intact controls. This increase was independent of prior adrenalectomy or corticosterone-replacement. These data demonstrate that TGF-beta gene expression increases in response to hippocampal deafferentation.

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Year:  1991        PMID： 2041055     DOI： 10.1002/jnr.490280114

Source DB:  PubMed          Journal:  J Neurosci Res        ISSN： 0360-4012            Impact factor:   4.164


  8 in total

1.  Association of a polymorphism of the transforming growth factor-beta1 gene with cerebral amyloid angiopathy.

Authors:  T Hamaguchi; S Okino; N Sodeyama; Y Itoh; A Takahashi; E Otomo; M Matsushita; H Mizusawa; M Yamada
Journal:  J Neurol Neurosurg Psychiatry       Date:  2005-05       Impact factor: 10.154

2.  Endogenous FGF-2 is important for cholinergic sprouting in the denervated hippocampus.

Authors:  A M Fagan; S T Suhr; C A Lucidi-Phillipi; D A Peterson; D M Holtzman; F H Gage
Journal:  J Neurosci       Date:  1997-04-01       Impact factor: 6.167

3.  Smad proteins differentially regulate transforming growth factor-β-mediated induction of chondroitin sulfate proteoglycans.

Authors:  Bala T S Susarla; Eric D Laing; Panpan Yu; Yasuhiro Katagiri; Herbert M Geller; Aviva J Symes
Journal:  J Neurochem       Date:  2011-10-03       Impact factor: 5.372

4.  Expression of transforming growth factor-beta 1 and interleukin-1 beta mRNA in rat brain following transient forebrain ischemia.

Authors:  C Wiessner; J Gehrmann; D Lindholm; R Töpper; G W Kreutzberg; K A Hossmann
Journal:  Acta Neuropathol       Date:  1993       Impact factor: 17.088

5.  Adrenalectomy promotes a permanent decrease of plasma corticoid levels and a transient increase of apoptosis and the expression of Transforming Growth Factor beta1 (TGF-beta1) in hippocampus: effect of a TGF-beta1 oligo-antisense.

Authors:  Javier A Bravo; Claudio S Parra; Sandor Arancibia; Sergio Andrés; Paola Morales; Mario Herrera-Marschitz; Luisa Herrera; Hernán E Lara; Jenny L Fiedler
Journal:  BMC Neurosci       Date:  2006-05-19       Impact factor: 3.288

6.  Transforming growth factor-beta 1 in the rat brain: increase after injury and inhibition of astrocyte proliferation.

Authors:  D Lindholm; E Castrén; R Kiefer; F Zafra; H Thoenen
Journal:  J Cell Biol       Date:  1992-04       Impact factor: 10.539

7.  Astrocyte-derived TGF-beta 2 and NGF differentially regulate neural recognition molecule expression by cultured astrocytes.

Authors:  B Saad; D B Constam; R Ortmann; M Moos; A Fontana; M Schachner
Journal:  J Cell Biol       Date:  1991-10       Impact factor: 10.539

8.  Enhanced expression of transforming growth factor beta 1 in the rat brain after a localized cerebral injury.

Authors:  A Logan; S A Frautschy; A M Gonzalez; M B Sporn; A Baird
Journal:  Brain Res       Date:  1992-08-07       Impact factor: 3.252
  8 in total

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