BACKGROUND: Maternal diet has been associated with fetal growth outcomes; however, evidence is scarce on the role of dietary quality. OBJECTIVE: The objective was to assess the effect of diet quality during the first trimester of pregnancy, as measured by the Alternate Healthy Eating Index (AHEI) adapted for pregnancy, on fetal growth. DESIGN: We studied 787 women and their newborns from a Spanish cohort study. Diet quality was assessed by using a modification of the AHEI. Adjusted birth weight, birth length, and head circumference were used as continuous outcomes. We used a customized model to define fetal growth restriction in weight, length, and head circumference. RESULTS: After adjustment of multivariate models, a positive association was observed between diet quality and adjusted birth weight and adjusted birth length. The greatest differences were found between the fourth and first quintiles of the AHEI. Newborns of women in the fourth quintile were on average 126.3 g (95% CI: 38.5, 213.9 g) heavier and 0.47 cm (95% CI: 0.08, 0.86 cm) longer than those in the lowest quintile (P for trend = 0.009 and 0.013, respectively). Women with the highest AHEI scores had a significantly lower risk of delivering a fetal growth-restricted infant for weight (odds ratio: 0.24; 95% CI: 0.10, 0.55; P for trend = 0.001) than did women in the lowest quintile, but this was not the case for fetal growth restriction in length (P for trend = 0.538) or head circumference (P for trend = 0.070). CONCLUSION: A high-quality diet in the first trimester of pregnancy is associated with birth size and the risk of fetal growth restriction.
BACKGROUND: Maternal diet has been associated with fetal growth outcomes; however, evidence is scarce on the role of dietary quality. OBJECTIVE: The objective was to assess the effect of diet quality during the first trimester of pregnancy, as measured by the Alternate Healthy Eating Index (AHEI) adapted for pregnancy, on fetal growth. DESIGN: We studied 787 women and their newborns from a Spanish cohort study. Diet quality was assessed by using a modification of the AHEI. Adjusted birth weight, birth length, and head circumference were used as continuous outcomes. We used a customized model to define fetal growth restriction in weight, length, and head circumference. RESULTS: After adjustment of multivariate models, a positive association was observed between diet quality and adjusted birth weight and adjusted birth length. The greatest differences were found between the fourth and first quintiles of the AHEI. Newborns of women in the fourth quintile were on average 126.3 g (95% CI: 38.5, 213.9 g) heavier and 0.47 cm (95% CI: 0.08, 0.86 cm) longer than those in the lowest quintile (P for trend = 0.009 and 0.013, respectively). Women with the highest AHEI scores had a significantly lower risk of delivering a fetal growth-restricted infant for weight (odds ratio: 0.24; 95% CI: 0.10, 0.55; P for trend = 0.001) than did women in the lowest quintile, but this was not the case for fetal growth restriction in length (P for trend = 0.538) or head circumference (P for trend = 0.070). CONCLUSION: A high-quality diet in the first trimester of pregnancy is associated with birth size and the risk of fetal growth restriction.
Authors: Lynn M Yee; Robert M Silver; David M Haas; Samuel Parry; Brian M Mercer; Jay Iams; Deborah Wing; Corette B Parker; Uma M Reddy; Ronald J Wapner; William A Grobman Journal: Am J Obstet Gynecol Date: 2020-01-23 Impact factor: 8.661
Authors: Jenica H Kakadia; Bhawani B Jain; Kyle Biggar; Austen Sutherland; Karen Nygard; Cun Li; Peter W Nathanielsz; Thomas Jansson; Madhulika B Gupta Journal: Am J Physiol Endocrinol Metab Date: 2020-08-03 Impact factor: 4.310
Authors: Pilar Navarro; John Mehegan; Celine M Murrin; Cecily C Kelleher; Catherine M Phillips Journal: Int J Obes (Lond) Date: 2020-08-22 Impact factor: 5.095
Authors: Carla Assaf-Balut; Nuria García de la Torre; Alejandra Duran; Manuel Fuentes; Elena Bordiú; Laura Del Valle; Cristina Familiar; Johanna Valerio; Inés Jiménez; Miguel A Herraiz; Nuria Izquierdo; María J Torrejon; Maria Ángeles Cuadrado; Isabel Ortega; Francisco J Illana; Isabelle Runkle; Paz de Miguel; Inmaculada Moraga; Carmen Montañez; Ana Barabash; Martín Cuesta; Miguel A Rubio; Alfonso L Calle-Pascual Journal: Ann Nutr Metab Date: 2018-12-14 Impact factor: 3.374
Authors: A L B Shapiro; J L Kaar; T L Crume; A P Starling; A M Siega-Riz; B M Ringham; D H Glueck; J M Norris; L A Barbour; J E Friedman; D Dabelea Journal: Int J Obes (Lond) Date: 2016-05-02 Impact factor: 5.095
Authors: Hugo Mendieta Zerón; Alejandro Parada Flores; Araceli Amaya Chávez; Adriana Garduño Alanís; María Del Carmen Colín Ferreyra; Jonnathan Guadalupe Santillán Benítez; Violeta Saraí Morales Castañeda; Ma Victoria Domínguez García Journal: Oman Med J Date: 2013-05