Literature DB >> 20408528

Copper-mediated cyclization-halogenation and cyclization-cyanation reactions of beta-hydroxyalkynes and o-alkynylphenols and anilines.

Nalivela Kumara Swamy1, Arife Yazici, Stephen G Pyne.   

Abstract

The CuX (X = I, Br, Cl, CN)-mediated cyclization-halogenation and cyclization-cyanation reactions of beta-hydroxyalkynes and o-alkynylphenol and -aniline derivatives give rise to 3-halo- and 3-cyanofuro[3,2-b]pyrroles, 3-iodo-, 3-bromo-, and 3-cyanobenzofurans, and 3-cyanoindoles, respectively.

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Year:  2010        PMID: 20408528     DOI: 10.1021/jo1005119

Source DB:  PubMed          Journal:  J Org Chem        ISSN: 0022-3263            Impact factor:   4.354


  5 in total

1.  Copper-catalyzed tandem reaction of 2-alkynylanilines with benzoquinones: efficient access to 3-indolylquinones.

Authors:  Raveendra Jillella; Chang Ho Oh
Journal:  RSC Adv       Date:  2018-06-15       Impact factor: 4.036

Review 2.  Direct cyanation, hydrocyanation, dicyanation and cyanofunctionalization of alkynes.

Authors:  Lifen Peng; Zhifang Hu; Hong Wang; Li Wu; Yinchun Jiao; Zilong Tang; Xinhua Xu
Journal:  RSC Adv       Date:  2020-03-10       Impact factor: 4.036

3.  One-pot gold-catalyzed synthesis of 3-silylethynyl indoles from unprotected o-alkynylanilines.

Authors:  Jonathan P Brand; Clara Chevalley; Jérôme Waser
Journal:  Beilstein J Org Chem       Date:  2011-05-04       Impact factor: 2.883

4.  Aminofluorination of 2-alkynylanilines: a Au-catalyzed entry to fluorinated indoles.

Authors:  Antonio Arcadi; Emanuela Pietropaolo; Antonello Alvino; Véronique Michelet
Journal:  Beilstein J Org Chem       Date:  2014-02-20       Impact factor: 2.883

5.  Facile synthesis of 2-substituted benzo[b]furans and indoles by copper-catalyzed intramolecular cyclization of 2-alkynyl phenols and tosylanilines.

Authors:  Zhouting Rong; Kexin Gao; Lei Zhou; Jianyuan Lin; Guoying Qian
Journal:  RSC Adv       Date:  2019-06-07       Impact factor: 4.036

  5 in total

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