Literature DB >> 20407588

Mouse Models for Type 1 Diabetes.

T L Van Belle1, P Taylor, M G von Herrath.   

Abstract

Our understanding of the genetics, aetiology and pathogenesis of Type 1 Diabetes (T1D) was propelled by the discovery of animal models of T1D in the late 1970s and early 1980s, particularly the non-obese diabetic (NOD) mouse. Since then, transgenic and gene-targeting technologies allowed the generation of many models with reduced genetic and pathogenic complexity. These models allowed researchers to zoom in on specific aspects of this complex disease. In this review, we provide an overview of currently available mouse models for T1D.

Entities:  

Year:  2009        PMID： 20407588      PMCID： PMC2855847          DOI： 10.1016/j.ddmod.2009.03.008

Source DB:  PubMed          Journal:  Drug Discov Today Dis Models        ISSN： 1740-6757


  40 in total

Review 1.  A comprehensive review of interventions in the NOD mouse and implications for translation.

Authors:  Lisl K M Shoda; Daniel L Young; Saroja Ramanujan; Chan C Whiting; Mark A Atkinson; Jeffrey A Bluestone; George S Eisenbarth; Diane Mathis; Aldo A Rossini; Scott E Campbell; Richard Kahn; Huub T C Kreuwel
Journal:  Immunity       Date:  2005-08       Impact factor: 31.745

2.  Elimination of maternally transmitted autoantibodies prevents diabetes in nonobese diabetic mice.

Authors:  Siri Atma W Greeley; Makoto Katsumata; Liping Yu; George S Eisenbarth; Daniel J Moore; Heidi Goodarzi; Clyde F Barker; Ali Naji; Hooman Noorchashm
Journal:  Nat Med       Date:  2002-04       Impact factor: 53.440

3.  The expression of influenza virus hemagglutinin in the pancreatic beta cells of transgenic mice results in autoimmune diabetes.

Authors:  L M Roman; L F Simons; R E Hammer; J F Sambrook; M J Gething
Journal:  Cell       Date:  1990-05-04       Impact factor: 41.582

4.  Maternal factors in a model of type 1 diabetes differentially affect the development of insulitis and overt diabetes in offspring.

Authors:  Yukiko Kagohashi; Jun Udagawa; Norio Abiru; Masakazu Kobayashi; Kenji Moriyama; Hiroki Otani
Journal:  Diabetes       Date:  2005-07       Impact factor: 9.461

5.  Ablation of "tolerance" and induction of diabetes by virus infection in viral antigen transgenic mice.

Authors:  P S Ohashi; S Oehen; K Buerki; H Pircher; C T Ohashi; B Odermatt; B Malissen; R M Zinkernagel; H Hengartner
Journal:  Cell       Date:  1991-04-19       Impact factor: 41.582

6.  Both the Lyt-2+ and L3T4+ T cell subsets are required for the transfer of diabetes in nonobese diabetic mice.

Authors:  B J Miller; M C Appel; J J O'Neil; L S Wicker
Journal:  J Immunol       Date:  1988-01-01       Impact factor: 5.422

7.  Relationship between pancreatic vesicular monoamine transporter 2 (VMAT2) and insulin expression in human pancreas.

Authors:  Yoshifumi Saisho; Paul E Harris; Alexandra E Butler; Ryan Galasso; Tatyana Gurlo; Robert A Rizza; Peter C Butler
Journal:  J Mol Histol       Date:  2008-09-13       Impact factor: 2.611

8.  Peripheral tolerance to an islet cell-specific hemagglutinin transgene affects both CD4+ and CD8+ T cells.

Authors:  D Lo; J Freedman; S Hesse; R D Palmiter; R L Brinster; L A Sherman
Journal:  Eur J Immunol       Date:  1992-04       Impact factor: 5.532

9.  Imaging the Beta-cell mass: why and how.

Authors:  Frantisek Saudek; Carl-Henrik Brogren; Srirang Manohar
Journal:  Rev Diabet Stud       Date:  2008-05-10

10.  CD8 T cell clones from young nonobese diabetic (NOD) islets can transfer rapid onset of diabetes in NOD mice in the absence of CD4 cells.

Authors:  F S Wong; I Visintin; L Wen; R A Flavell; C A Janeway
Journal:  J Exp Med       Date:  1996-01-01       Impact factor: 14.307
View more
  37 in total

1.  Nrf2 represses the onset of type 1 diabetes in non-obese diabetic mice.

Authors:  Yoko Yagishita; Akira Uruno; Dionysios V Chartoumpekis; Thomas W Kensler; Masayuki Yamamoto
Journal:  J Endocrinol       Date:  2019-01-01       Impact factor: 4.286

2.  Regulatory T cells control diabetes without compromising acute anti-viral defense.

Authors:  Carmen Baca Jones; Philippe P Pagni; Georgia Fousteri; Sowbarnika Sachithanantham; Amy Dave; Teresa Rodriguez-Calvo; Jacqueline Miller; Matthias von Herrath
Journal:  Clin Immunol       Date:  2014-05-22       Impact factor: 3.969

Review 3.  Unraveling pancreatic islet biology by quantitative proteomics.

Authors:  Jian-Ying Zhou; Geoffrey P Dann; Chong Wee Liew; Richard D Smith; Rohit N Kulkarni; Wei-Jun Qian
Journal:  Expert Rev Proteomics       Date:  2011-08       Impact factor: 3.940

4.  A murine model for non-alcoholic steatohepatitis showing evidence of association between diabetes and hepatocellular carcinoma.

Authors:  Masato Fujii; Yuichiro Shibazaki; Kyoko Wakamatsu; Yutaka Honda; Yusuke Kawauchi; Kenji Suzuki; Somasundaram Arumugam; Kenichi Watanabe; Takafumi Ichida; Hitoshi Asakura; Hiroyuki Yoneyama
Journal:  Med Mol Morphol       Date:  2013-02-22       Impact factor: 2.309

5.  Absence of leptin triggers type 1 diabetes.

Authors:  Bettina Mittendorfer; Samuel Klein
Journal:  Nat Med       Date:  2014-07       Impact factor: 53.440

Review 6.  Mouse models of diabetic neuropathy.

Authors:  Phillipe D O'Brien; Stacey A Sakowski; Eva L Feldman
Journal:  ILAR J       Date:  2014

7.  The Presence and Preferential Activation of Regulatory T Cells Diminish Adoptive Transfer of Autoimmune Diabetes by Polyclonal Nonobese Diabetic (NOD) T Cell Effectors into NSG versus NOD-scid Mice.

Authors:  Maximiliano Presa; Yi-Guang Chen; Alexandra E Grier; Edward H Leiter; Michael A Brehm; Dale L Greiner; Leonard D Shultz; David V Serreze
Journal:  J Immunol       Date:  2015-08-17       Impact factor: 5.422

8.  Emetine Di-HCl Attenuates Type 1 Diabetes Mellitus in Mice.

Authors:  LaQueta K Hudson; Meghan E Dancho; Jianhua Li; Johanna B Bruchfeld; Ahmed A Ragab; Mingzhu M He; Meaghan Bragg; Delaney Lenaghan; Michael D Quinn; Jason R Fritz; Matthew V Tanzi; Harold A Silverman; William M Hanes; Yaakov A Levine; Valentin A Pavlov; Peder S Olofsson; Jesse Roth; Yousef Al-Abed; Ulf Andersson; Kevin J Tracey; Sangeeta S Chavan
Journal:  Mol Med       Date:  2016-06-10       Impact factor: 6.354

9.  Elimination of T cell reactivity to pancreatic β cells and partial preservation of β cell activity by peptide blockade of LFA-1:ICAM-1 interaction in the NOD mouse model.

Authors:  Abby L Dotson; Lesya Novikova; Lisa Stehno-Bittel; Stephen H Benedict
Journal:  Clin Immunol       Date:  2013-05-09       Impact factor: 3.969

10.  Diabetes-related impairment in bone strength is established early in the life course.

Authors:  Krista Casazza; Lynae J Hanks; Gregory A Clines; Hubert M Tse; Alan W Eberhardt
Journal:  World J Diabetes       Date:  2013-08-15
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.