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Literature DB >> 20405881

Oxepinochromenones, furochromenone, and their putative precursors from the endolichenic fungus Coniochaeta sp.

Yinchao Wang¹, Zhihui Zheng, Shuchun Liu, Hua Zhang, Erwei Li, Liangdong Guo, Yongsheng Che.

Abstract

Six new polyketides including four oxepinochromenones, conioxepinols A-D (1-4), one furochromenone, coniofurol A (5), and one xanthone, conioxanthone A (6), have been isolated from the crude extract of the endolichenic fungus Coniochaeta sp. The absolute configurations of C-7 in 1 and the 7,8-diol moiety in 3 were assigned using the modified Mosher's and Snatzke's method, respectively, whereas that of C-8 in 5 was deduced via the circular dichroism data of the [Rh(2)(OCOCF(3))(4)] complex. Compounds 2-4 showed modest cytotoxicity against a small panel of human tumor cell lines.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 2010 PMID： 20405881 DOI： 10.1021/np100071z

Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050

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Cited

12 in total

1. Geopyxins A-E, ent-kaurane diterpenoids from endolichenic fungal strains Geopyxis aff. majalis and Geopyxis sp. AZ0066: structure-activity relationships of geopyxins and their analogues.

Authors: E M Kithsiri Wijeratne; Bharat P Bashyal; Manping X Liu; Danilo D Rocha; G M Kamal B Gunaherath; Jana M U'Ren; Malkanthi K Gunatilaka; A Elizabeth Arnold; Luke Whitesell; A A Leslie Gunatilaka
Journal: J Nat Prod Date: 2012-01-20 Impact factor: 4.050

2. Red soils harbor diverse culturable actinomycetes that are promising sources of novel secondary metabolites.

Authors: Xiaoxuan Guo; Ning Liu; Xiaomin Li; Yun Ding; Fei Shang; Yongsheng Gao; Jisheng Ruan; Ying Huang
Journal: Appl Environ Microbiol Date: 2015-02-27 Impact factor: 4.792

3. An endophytic Coniochaeta velutina producing broad spectrum antimycotics.

Authors: Jie Xie; Gary A Strobel; Tao Feng; Huishuang Ren; Morgan T Mends; Zeyang Zhou; Brad Geary
Journal: J Microbiol Date: 2015-05-30 Impact factor: 3.422

4. General synthetic approach to functionalized dihydrooxepines.

Authors: K C Nicolaou; Ruocheng Yu; Lei Shi; Quan Cai; Min Lu; Philipp Heretsch
Journal: Org Lett Date: 2013-04-04 Impact factor: 6.005

5. Effect of Isolation Conditions on Diversity of Endolichenic Fungal Communities from a Foliose Lichen, Parmotrema tinctorum.

Authors: Ji Ho Yang; Seung-Yoon Oh; Wonyong Kim; Jung-Jae Woo; Hyeonjae Kim; Jae-Seoun Hur
Journal: J Fungi (Basel) Date: 2021-04-26

Oxepinochromenones, furochromenone, and their putative precursors from the endolichenic fungus Coniochaeta sp.

1. Geopyxins A-E, ent-kaurane diterpenoids from endolichenic fungal strains Geopyxis aff. majalis and Geopyxis sp. AZ0066: structure-activity relationships of geopyxins and their analogues.

2. Red soils harbor diverse culturable actinomycetes that are promising sources of novel secondary metabolites.

3. An endophytic Coniochaeta velutina producing broad spectrum antimycotics.

4. General synthetic approach to functionalized dihydrooxepines.

5. Effect of Isolation Conditions on Diversity of Endolichenic Fungal Communities from a Foliose Lichen, Parmotrema tinctorum.

6. Polyketides with Immunosuppressive Activities from Mangrove Endophytic Fungus Penicillium sp. ZJ-SY₂.

Review 7. Fungal Diversity in Lichens: From Extremotolerance to Interactions with Algae.

8. New Chromones from a Marine-Derived Fungus, Arthrinium sp., and Their Biological Activity.

9. Orthogonal Method for Double-Bond Placement via Ozone-Induced Dissociation Mass Spectrometry (OzID-MS).

10. Potential Antiviral Xanthones from a Coastal Saline Soil Fungus Aspergillus iizukae.