Literature DB >> 20405852

Cell-trappable fluorescent probes for nitric oxide visualization in living cells.

Michael D Pluth1, Lindsey E McQuade, Stephen J Lippard.   

Abstract

Two new cell-trappable fluorescent probes for nitric oxide (NO) are reported based on either incorporation of hydrolyzable esters or conjugation to aminodextran polymers. Both probes are highly selective for NO over other reactive oxygen and nitrogen species (RONS). The efficacy of these probes for the fluorescence imaging of nitric oxide produced endogenously in Raw 264.7 cells is demonstrated.

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Year:  2010        PMID： 20405852      PMCID： PMC2871341          DOI： 10.1021/ol1006289

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  30 in total

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