Wissam E Mattar1, Biju K Alex, Averell H Sherker. 1. Division of Gastroenterology and Hepatology, Washington Hospital Center, 110 Irving St NW, Rm no 3A-3, Washington, DC 20010, USA. wissam.e.mattar@medstar.net
Abstract
INTRODUCTION: We report the first case of immunophenotypically confirmed primary hepatic Burkitt lymphoma presenting with acute liver failure. The patient survived following an aggressive diagnostic approach followed by emergent chemotherapy. DISCUSSION: Data from the primary hepatic non-Hodgkin lymphoma literature show a survival rate of 87% at 5 years with combination regimens of chemotherapy. However, mortality rate in this population is 85% in patients with acute liver failure. CONCLUSION: Primary hepatic Burkitt lymphoma may respond well to emergent chemotherapy even in the setting of acute liver failure.
INTRODUCTION: We report the first case of immunophenotypically confirmed primary hepatic Burkitt lymphoma presenting with acute liver failure. The patient survived following an aggressive diagnostic approach followed by emergent chemotherapy. DISCUSSION: Data from the primary hepatic non-Hodgkin lymphoma literature show a survival rate of 87% at 5 years with combination regimens of chemotherapy. However, mortality rate in this population is 85% in patients with acute liver failure. CONCLUSION:Primary hepatic Burkitt lymphoma may respond well to emergent chemotherapy even in the setting of acute liver failure.
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