INTRODUCTION: Gallbladder carcinoma has been associated with various paraneoplastic syndromes. These may be the presenting manifestations that lead the clinician to a diagnosis. CASE REPORT: We report a case of small cell gallbladder carcinoma complicated by paraneoplastic hyponatremia. The hyponatremia was further exacerbated by platinum-based chemotherapy. DISCUSSION: There have previously been no reports of paraneoplastic hyponatremia in gallbladder carcinoma. We discuss the management of this problem and also provide a short literature review on the other paraneoplastic syndromes associated with gallbladder carcinoma. CONCLUSION: Symptoms and signs of gallbladder cancer may be insidious. Thorough workup is needed if the patient presents with symptoms and signs of a paraneoplastic syndrome.
INTRODUCTION:Gallbladder carcinoma has been associated with various paraneoplastic syndromes. These may be the presenting manifestations that lead the clinician to a diagnosis. CASE REPORT: We report a case of small cell gallbladder carcinoma complicated by paraneoplastic hyponatremia. The hyponatremia was further exacerbated by platinum-based chemotherapy. DISCUSSION: There have previously been no reports of paraneoplastic hyponatremia in gallbladder carcinoma. We discuss the management of this problem and also provide a short literature review on the other paraneoplastic syndromes associated with gallbladder carcinoma. CONCLUSION: Symptoms and signs of gallbladder cancer may be insidious. Thorough workup is needed if the patient presents with symptoms and signs of a paraneoplastic syndrome.
Authors: T Ziadi; A Alahyane; M El Fahssi; R Makhmari; A Elhjouji; H Baba; C Ould Jiddou; I Nafae; A Mejdane; A Bounaim; A Ait Ali; A Zentar; A Hommadi; K Sair Journal: Gastroenterol Clin Biol Date: 2009-09-17
Authors: Mutahir A Tunio; Mushabbab Alasiri; Asma Mohammed F Ali; Eyad Fawzi Alsaeed; Muhammad Shuja; Hanadi Fatani Journal: Case Rep Gastrointest Med Date: 2013-12-14
Authors: Paolo Aiello; Francesco Aragona; Valentina Territo; Anna Maria Caruso; Rosalia Patti; Salvatore Buscemi; Gaetano Di Vita Journal: Case Rep Surg Date: 2014-09-25