Literature DB >> 20404820

Drug discovery: engineering drug combinations.

Scott J Dixon, Brent R Stockwell.   

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Year:  2010        PMID： 20404820      PMCID： PMC3048766          DOI： 10.1038/nchembio.353

Source DB:  PubMed          Journal:  Nat Chem Biol        ISSN： 1552-4450            Impact factor:   15.040


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  10 in total

1.  Dynamic proteomics in individual human cells uncovers widespread cell-cycle dependence of nuclear proteins.

Authors:  Alex Sigal; Ron Milo; Ariel Cohen; Naama Geva-Zatorsky; Yael Klein; Inbal Alaluf; Naamah Swerdlin; Natalie Perzov; Tamar Danon; Yuvalal Liron; Tal Raveh; Anne E Carpenter; Galit Lahav; Uri Alon
Journal:  Nat Methods       Date:  2006-07       Impact factor: 28.547

Review 2.  Proteins, drug targets and the mechanisms they control: the simple truth about complex networks.

Authors:  Robyn P Araujo; Lance A Liotta; Emanuel F Petricoin
Journal:  Nat Rev Drug Discov       Date:  2007-11       Impact factor: 84.694

3.  Dynamic proteomics of individual cancer cells in response to a drug.

Authors:  A A Cohen; N Geva-Zatorsky; E Eden; M Frenkel-Morgenstern; I Issaeva; A Sigal; R Milo; C Cohen-Saidon; Y Liron; Z Kam; L Cohen; T Danon; N Perzov; U Alon
Journal:  Science       Date:  2008-11-20       Impact factor: 47.728

Review 4.  Mechanisms of drug combinations: interaction and network perspectives.

Authors:  Jia Jia; Feng Zhu; Xiaohua Ma; Zhiwei Cao; Zhiwei W Cao; Yixue Li; Yixue X Li; Yu Zong Chen
Journal:  Nat Rev Drug Discov       Date:  2009-02       Impact factor: 84.694

Review 5.  Progress towards personalized medicine.

Authors:  Stewart Bates
Journal:  Drug Discov Today       Date:  2009-11-13       Impact factor: 7.851

6.  Symbiotic Streptomycetes provide antibiotic combination prophylaxis for wasp offspring.

Authors:  Johannes Kroiss; Martin Kaltenpoth; Bernd Schneider; Maria-Gabriele Schwinger; Christian Hertweck; Ravi Kumar Maddula; Erhard Strohm; Ales Svatos
Journal:  Nat Chem Biol       Date:  2010-02-28       Impact factor: 15.040

7.  Protein dynamics in drug combinations: a linear superposition of individual-drug responses.

Authors:  Naama Geva-Zatorsky; Erez Dekel; Ariel A Cohen; Tamar Danon; Lydia Cohen; Uri Alon
Journal:  Cell       Date:  2010-03-05       Impact factor: 41.582

Review 8.  Treatment of non-Hodgkin's lymphoma.

Authors:  J O Armitage
Journal:  N Engl J Med       Date:  1993-04-08       Impact factor: 91.245

9.  Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators.

Authors:  F J Palella; K M Delaney; A C Moorman; M O Loveless; J Fuhrer; G A Satten; D J Aschman; S D Holmberg
Journal:  N Engl J Med       Date:  1998-03-26       Impact factor: 91.245

10.  Chemical combination effects predict connectivity in biological systems.

Authors:  Joseph Lehár; Grant R Zimmermann; Andrew S Krueger; Raymond A Molnar; Jebediah T Ledell; Adrian M Heilbut; Glenn F Short; Leanne C Giusti; Garry P Nolan; Omar A Magid; Margaret S Lee; Alexis A Borisy; Brent R Stockwell; Curtis T Keith
Journal:  Mol Syst Biol       Date:  2007-02-27       Impact factor: 11.429
  10 in total
  2 in total

1.  Network-based drug discovery by integrating systems biology and computational technologies.

Authors:  Elaine L Leung; Zhi-Wei Cao; Zhi-Hong Jiang; Hua Zhou; Liang Liu
Journal:  Brief Bioinform       Date:  2012-08-09       Impact factor: 11.622

2.  Effect of a fixed combination of nimodipine and betahistine versus betahistine as monotherapy in the long-term treatment of Ménière's disease: a 10-year experience.

Authors:  D Monzani; M R Barillari; M Alicandri Ciufelli; E Aggazzotti Cavazza; V Neri; L Presutti; E Genovese
Journal:  Acta Otorhinolaryngol Ital       Date:  2012-12       Impact factor: 2.124
  2 in total

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