Literature DB >> 2040361

Interleukin-6 stimulates prostaglandin production by human amnion and decidual cells.

M D Mitchell1, D J Dudley, S S Edwin, S L Schiller.   

Abstract

The effects of interleukin-6 on prostaglandin production by cells from two key sources on intrauterine prostaglandin, i.e. amnion and decidua, have been evaluated. Interleukin-6 induced a concentration-related increase in prostaglandin production by amnion and decidual cells. The concentrations of interleukin-6 required for this stimulatory action are within the range measured in amniotic fluid of women with intrauterine infections and preterm labor. Hence, interleukin-6 may contribute to the mechanism of preterm labor under these conditions.

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Year:  1991        PMID： 2040361     DOI： 10.1016/0014-2999(91)90090-d

Source DB:  PubMed          Journal:  Eur J Pharmacol        ISSN： 0014-2999            Impact factor:   4.432


  26 in total

1.  The regulation of prostaglandin output from term intact fetal membranes by anti-inflammatory cytokines.

Authors:  N L Brown; S A Alvi; M G Elder; P R Bennett; M H Sullivan
Journal:  Immunology       Date:  2000-01       Impact factor: 7.397

2.  Regulation of interleukin-6 expression in human decidual cells and its potential role in chorioamnionitis.

Authors:  Charles J Lockwood; William K Murk; Umit A Kayisli; Lynn F Buchwalder; S Joseph Huang; Felice Arcuri; Min Li; Arun Gopinath; Frederick Schatz
Journal:  Am J Pathol       Date:  2010-08-19       Impact factor: 4.307

3.  A molecular signature of an arrest of descent in human parturition.

Authors:  Pooja Mittal; Roberto Romero; Adi L Tarca; Sorin Draghici; Chia-Ling Nhan-Chang; Tinnakorn Chaiworapongsa; John Hotra; Ricardo Gomez; Juan Pedro Kusanovic; Deug-Chan Lee; Chong Jai Kim; Sonia S Hassan
Journal:  Am J Obstet Gynecol       Date:  2011-02       Impact factor: 8.661

4.  IL-6 trans-signaling system in intra-amniotic inflammation, preterm birth, and preterm premature rupture of the membranes.

Authors:  Sarah Y Lee; Irina A Buhimschi; Antonette T Dulay; Unzila A Ali; Guomao Zhao; Sonya S Abdel-Razeq; Mert O Bahtiyar; Stephen F Thung; Edmund F Funai; Catalin S Buhimschi
Journal:  J Immunol       Date:  2011-01-31       Impact factor: 5.422

Review 5.  Use of nonhuman primate models to investigate mechanisms of infection-associated preterm birth.

Authors:  K M Adams Waldorf; C E Rubens; M G Gravett
Journal:  BJOG       Date:  2010-10-13       Impact factor: 6.531

6.  Characterization of the myometrial transcriptome and biological pathways of spontaneous human labor at term.

Authors:  Pooja Mittal; Roberto Romero; Adi L Tarca; Juan Gonzalez; Sorin Draghici; Yi Xu; Zhong Dong; Chia-Ling Nhan-Chang; Tinnakorn Chaiworapongsa; Stephen Lye; Juan Pedro Kusanovic; Leonard Lipovich; Shali Mazaki-Tovi; Sonia S Hassan; Sam Mesiano; Chong Jai Kim
Journal:  J Perinat Med       Date:  2010-07-14       Impact factor: 1.901

7.  Relaxin augments the inflammatory IL6 response in the choriodecidua.

Authors:  J S Horton; S Y Yamamoto; G D Bryant-Greenwood
Journal:  Placenta       Date:  2012-03-03       Impact factor: 3.481

8.  Immunomodulators plus antibiotics delay preterm delivery after experimental intraamniotic infection in a nonhuman primate model.

Authors:  Michael G Gravett; Kristina M Adams; Drew W Sadowsky; Alexandra R Grosvenor; Steven S Witkin; Michael K Axthelm; Miles J Novy
Journal:  Am J Obstet Gynecol       Date:  2007-11       Impact factor: 8.661

9.  Resistance to lipopolysaccharide-induced preterm delivery mediated by regulatory T cell function in mice.

Authors:  Peyman Bizargity; Roxana Del Rio; Mark Phillippe; Cory Teuscher; Elizabeth A Bonney
Journal:  Biol Reprod       Date:  2009-01-14       Impact factor: 4.285

Review 10.  Human fetal membranes at term: Dead tissue or signalers of parturition?

Authors:  Ramkumar Menon
Journal:  Placenta       Date:  2016-05-29       Impact factor: 3.481
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