Literature DB >> 20402984

Testing for cannabis in the work-place: a review of the evidence.

Scott Macdonald1, Wayne Hall, Paul Roman, Tim Stockwell, Michelle Coghlan, Sverre Nesvaag.   

Abstract

BACKGROUND: Urinalysis testing in the work-place has been adopted widely by employers in the United States to deter employee drug use and promote 'drug-free' work-places. In other countries, such as Canada, testing is focused more narrowly on identifying employees whose drug use puts the safety of others at risk. AIMS: We review 20 years of published literature on questions relevant to the objectives of work-place drug testing (WPDT), with a special emphasis on cannabis, the most commonly detected drug.
RESULTS: We conclude (i) that the acute effects of smoking cannabis impair performance for a period of about 4 hours; (ii) long-term heavy use of cannabis can impair cognitive ability, but it is not clear that heavy cannabis users represent a meaningful job safety risk unless using before work or on the job; (iii) urine tests have poor validity and low sensitivity to detect employees who represent a safety risk; (iv) drug testing is related to reductions in the prevalence of cannabis positive tests among employees, but this might not translate into fewer cannabis users; and (v) urinalysis has not been shown to have a meaningful impact on job injury/accident rates.
CONCLUSIONS: Urinalysis testing is not recommended as a diagnostic tool to identify employees who represent a job safety risk from cannabis use. Blood testing for active tetrahydrocannabinol (THC) can be considered by employers who wish to identify employees whose performance may be impaired by their cannabis use.

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Year:  2010        PMID: 20402984     DOI: 10.1111/j.1360-0443.2009.02808.x

Source DB:  PubMed          Journal:  Addiction        ISSN: 0965-2140            Impact factor:   6.526


  14 in total

1.  Pharmacokinetic Characterization of 11-nor-9-carboxy-Δ9-tetrahydrocannabinol in Urine Following Acute Oral Cannabis Ingestion in Healthy Adults.

Authors:  Nicolas J Schlienz; Edward J Cone; Evan S Herrmann; Natalie A Lembeck; John M Mitchell; George E Bigelow; Ronald Flegel; Charles P LoDico; Eugene D Hayes; Ryan Vandrey
Journal:  J Anal Toxicol       Date:  2018-05-01       Impact factor: 3.367

Review 2.  The why behind the high: determinants of neurocognition during acute cannabis exposure.

Authors:  Johannes G Ramaekers; Natasha L Mason; Lilian Kloft; Eef L Theunissen
Journal:  Nat Rev Neurosci       Date:  2021-05-27       Impact factor: 34.870

3.  Thermographic detection and quantification of THC in oral fluid at unprecedented low concentrations.

Authors:  Damber Thapa; Nakisa Samadi; Nisarg Patel; Nima Tabatabaei
Journal:  Biomed Opt Express       Date:  2020-03-24       Impact factor: 3.732

4.  Oral fluid/plasma cannabinoid ratios following controlled oral THC and smoked cannabis administration.

Authors:  Dayong Lee; Ryan Vandrey; Garry Milman; Mateus Bergamaschi; Damodara R Mendu; Jeannie A Murray; Allan J Barnes; Marilyn A Huestis
Journal:  Anal Bioanal Chem       Date:  2013-07-06       Impact factor: 4.142

5.  Urinary Excretion Profile of 11-Nor-9-Carboxy-Δ9-Tetrahydrocannabinol (THCCOOH) Following Smoked and Vaporized Cannabis Administration in Infrequent Cannabis Users.

Authors:  Tory R Spindle; Edward J Cone; Nicolas J Schlienz; John M Mitchell; George E Bigelow; Ronald Flegel; Eugene Hayes; Ryan Vandrey
Journal:  J Anal Toxicol       Date:  2020-01-07       Impact factor: 3.367

Review 6.  The negative impact of attention-deficit/hyperactivity disorder on occupational health in adults and adolescents.

Authors:  Thomas Küpper; Jan Haavik; Hans Drexler; Josep Antoni Ramos-Quiroga; Detlef Wermelskirchen; Christin Prutz; Barbara Schauble
Journal:  Int Arch Occup Environ Health       Date:  2012-07-03       Impact factor: 3.015

7.  Clinical perspectives on medical marijuana (cannabis) for neurologic disorders.

Authors:  Terry D Fife; Heidi Moawad; Constantine Moschonas; Katie Shepard; Nancy Hammond
Journal:  Neurol Clin Pract       Date:  2015-08

Review 8.  Current knowledge on cannabinoids in oral fluid.

Authors:  Dayong Lee; Marilyn A Huestis
Journal:  Drug Test Anal       Date:  2013-08-25       Impact factor: 3.345

9.  Simultaneous quantification of 11 cannabinoids and metabolites in human urine by liquid chromatography tandem mass spectrometry using WAX-S tips.

Authors:  Maria Andersson; Karl B Scheidweiler; Cristina Sempio; Allan J Barnes; Marilyn A Huestis
Journal:  Anal Bioanal Chem       Date:  2016-07-15       Impact factor: 4.142

10.  Cannabis cue-induced brain activation correlates with drug craving in limbic and visual salience regions: preliminary results.

Authors:  Evonne J Charboneau; Mary S Dietrich; Sohee Park; Aize Cao; Tristan J Watkins; Jennifer U Blackford; Margaret M Benningfield; Peter R Martin; Maciej S Buchowski; Ronald L Cowan
Journal:  Psychiatry Res       Date:  2013-09-12       Impact factor: 3.222

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