Literature DB >> 20401398

Towards click bioconjugations on cube-octameric silsesquioxane scaffolds.

Sebastian Fabritz1, Dirk Heyl, Viktor Bagutski, Martin Empting, Eckhard Rikowski, Holm Frauendorf, Ildiko Balog, Wolf-Dieter Fessner, Jörg J Schneider, Olga Avrutina, Harald Kolmar.   

Abstract

Cube-octameric silsesquioxane (POSS) based conjugation scaffolds for copper catalysed azide-alkyne [3+2] cycloaddition are reported. The synthetic route to octaazido and octaalkyno functionalised POSS templates without cage rearrangements is described. A set of click couplings is conducted including the first effective conjugation with a fully unprotected functional peptide towards a POSS assembled peptide octamer.

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Year:  2010        PMID： 20401398     DOI： 10.1039/b923393h

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  3 in total

1.  Membrane-specific spin trap, 5-dodecylcarbamoyl-5-N-dodecylacetamide-1-pyroline-N-oxide (diC12PO): theoretical, bioorthogonal fluorescence imaging and EPR studies.

Authors:  Colwyn A Headley; Claire N Hoffman; Juliana M Freisen; Yongbin Han; Joseph M Macklin; Jay L Zweier; Antal Rockenbauer; Jeff Kuret; Frederick A Villamena
Journal:  Org Biomol Chem       Date:  2019-07-22       Impact factor: 3.876

2.  Branched Polyhedral Oligomeric Silsesquioxane Nanoparticles Prepared via Strain-Promoted 1,3-Dipolar Cycloadditions.

Authors:  Petr A Ledin; Weinan Xu; Frédéric Friscourt; Geert-Jan Boons; Vladimir V Tsukruk
Journal:  Langmuir       Date:  2015-07-14       Impact factor: 3.882

Review 3.  Use of Polyhedral Oligomeric Silsesquioxane (POSS) in Drug Delivery, Photodynamic Therapy and Bioimaging.

Authors:  Paula Loman-Cortes; Tamanna Binte Huq; Juan L Vivero-Escoto
Journal:  Molecules       Date:  2021-10-26       Impact factor: 4.411
  3 in total

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