Literature DB >> 20401256

Acetaminophen and ibuprofen in the management of fever and mild to moderate pain in children.

H N McCullough1.   

Abstract

Acetaminophen has become the non-narcotic of choice for children because of concerns regarding the connection between acetylsalicylic acid exposure and Reye's syndrome. Ibuprofen, recently granted over-the-counter status for children over two years of age, offers another choice for treatment. The efficacy and safety of both drugs have been studied in numerous clinical trials. This paper reviews the published evidence about the efficacy and safety of acetaminophen and ibuprofen with regard to treating fever and mild to moderate pain in children.

Entities:  

Keywords:  Acetaminophen; Fever; Ibuprofen; Pain

Year:  1998        PMID： 20401256      PMCID： PMC2851344          DOI： 10.1093/pch/3.4.246

Source DB:  PubMed          Journal:  Paediatr Child Health        ISSN： 1205-7088            Impact factor:   2.253


  38 in total

1.  Acetaminophen overdose with therapeutic intent.

Authors:  G L Kearns; J S Leeder; G S Wasserman
Journal:  J Pediatr       Date:  1998-01       Impact factor: 4.406

Review 2.  Ibuprofen and paracetamol: relative safety in non-prescription dosages.

Authors:  K D Rainsford; S C Roberts; S Brown
Journal:  J Pharm Pharmacol       Date:  1997-04       Impact factor: 3.765

Review 3.  Therapeutic misadventures with acetaminophen: hepatoxicity after multiple doses in children.

Authors:  J E Heubi; M B Barbacci; H J Zimmerman
Journal:  J Pediatr       Date:  1998-01       Impact factor: 4.406

4.  American Academy of Pediatrics Committee on Infectious Diseases: Family history of convulsions in candidates for immunization with pertussis-containing vaccines (diphtheria, tetanus, pertussis).

Authors: 
Journal:  Pediatrics       Date:  1987-11       Impact factor: 7.124

5.  Antipyretic effectiveness of acetaminophen in febrile seizures: ongoing prophylaxis versus sporadic usage.

Authors:  D Schnaiderman; E Lahat; T Sheefer; M Aladjem
Journal:  Eur J Pediatr       Date:  1993-09       Impact factor: 3.183

6.  Perioperative effects of oral ketorolac and acetaminophen in children undergoing bilateral myringotomy.

Authors:  M F Watcha; M Ramirez-Ruiz; P F White; M B Jones; R G Lagueruela; R P Terkonda
Journal:  Can J Anaesth       Date:  1992-09       Impact factor: 5.063

7.  Single-dose, placebo-controlled comparative study of ibuprofen and acetaminophen antipyresis in children.

Authors:  J T Wilson; R D Brown; G L Kearns; V F Eichler; V A Johnson; K M Bertrand; B A Lowe
Journal:  J Pediatr       Date:  1991-11       Impact factor: 4.406

8.  Analgesia after bilateral myringotomy and placement of pressure equalization tubes in children: acetaminophen versus acetaminophen with codeine.

Authors:  J D Tobias; S Lowe; S Hersey; G E Rasmussen; J Werkhaven
Journal:  Anesth Analg       Date:  1995-09       Impact factor: 5.108

9.  Comparative efficacy and tolerance of ibuprofen syrup and acetaminophen syrup in children with pyrexia associated with infectious diseases and treated with antibiotics.

Authors:  E Autret; G Breart; A P Jonville; S Courcier; C Lassale; J M Goehrs
Journal:  Eur J Clin Pharmacol       Date:  1994       Impact factor: 2.953

10.  An assessment of the safety of pediatric ibuprofen. A practitioner-based randomized clinical trial.

Authors:  S M Lesko; A A Mitchell
Journal:  JAMA       Date:  1995 Mar 22-29       Impact factor: 56.272
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  6 in total

1.  Acute pain management: acetaminophen and ibuprofen are often under-dosed.

Authors:  Gregorio P Milani; Franca Benini; Laura Dell'Era; Davide Silvagni; Alberto F Podestà; Rossella Letizia Mancusi; Emilio F Fossali
Journal:  Eur J Pediatr       Date:  2017-06-10       Impact factor: 3.183

Review 2.  Safety and outcome of treatment of metastatic melanoma using 3-bromopyruvate: a concise literature review and case study.

Authors:  Salah Mohamed El Sayed; Walaa Gamal Mohamed; Minnat-Allah Hassan Seddik; Al-Shimaa Ahmed Ahmed; Asmaa Gamal Mahmoud; Wael Hassan Amer; Manal Mohamed Helmy Nabo; Ahmed Roshdi Hamed; Nagwa Sayed Ahmed; Ali Abdel-Rahman Abd-Allah
Journal:  Chin J Cancer       Date:  2014-03-14

Review 3.  The role of oxidative stress, inflammation and acetaminophen exposure from birth to early childhood in the induction of autism.

Authors:  William Parker; Chi Dang Hornik; Staci Bilbo; Zoie E Holzknecht; Lauren Gentry; Rasika Rao; Shu S Lin; Martha R Herbert; Cynthia D Nevison
Journal:  J Int Med Res       Date:  2017-03-16       Impact factor: 1.671

4.  Reducing Time to Pain Medication Administration for Pediatric Patients with Long Bone Fractures in the Emergency Department.

Authors:  Sarah S Schuman; Rebecca B Regen; Lindsay H Stuart; Camden Harrell; Tamekia L Jones; Barbara M Stewart; Allyson M Berg; Mindy Longjohn; Rudy J Kink
Journal:  Pediatr Qual Saf       Date:  2018-11-15

5.  Randomized comparative trial of efficacy of paracetamol, ibuprofen and paracetamol-ibuprofen combination for treatment of febrile children.

Authors:  Falgun Indravadan Vyas; Devang Ashwinkumar Rana; Piyush M Patel; Varsha Jitendra Patel; Rekha H Bhavsar
Journal:  Perspect Clin Res       Date:  2014-01

6.  Symptomatic Management of Fever in Children: A National Survey of Healthcare Professionals' Practices in France.

Authors:  Nathalie Bertille; Gerard Pons; Babak Khoshnood; Elisabeth Fournier-Charrière; Martin Chalumeau
Journal:  PLoS One       Date:  2015-11-23       Impact factor: 3.240
  6 in total

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