STUDY OBJECTIVE: To evaluate the influence of nasal oxygen (O(2)) administration on the duration of arterial oxygen saturation (SpO(2)) >or=95% during simulated difficult laryngoscopy in obese patients. DESIGN: Prospective, randomized, controlled trial. SETTING:University hospital. PATIENTS: 30 obese men undergoing general anesthesia. INTERVENTIONS: After thorough preoxygenation, and using total intravenous anesthesia, simulated difficult laryngoscopy was performed, with half the patients receiving additional nasal O(2) during apnea. MEASUREMENTS: Duration of SpO(2) >or=95% was measured up to a maximum of 6 minutes. Lowest SpO(2) values and time to regain 100% SpO(2) (resaturation time) also were recorded. MAIN RESULTS: Nasal O(2) administration was associated with significant prolongation of SpO(2) >or=95% time (5.29 +/- 1.02 vs. 3.49 +/- 1.33 min, mean +/- SD), a significant increase in patients with SpO(2) >or=95% apnea at 6 minutes (8 vs. one pt), and significantly higher minimum SpO(2) (94.3 +/- 4.4% vs. 87.7 +/- 9.3%). Resaturation times were no different between the groups. CONCLUSIONS: Nasal O(2) administration is associated with significant increases in frequency and duration of SpO(2) >or=95%, and higher minimum SpO(2) during prolonged laryngoscopy in obese patients. (c) 2010 Elsevier Inc. All rights reserved.
RCT Entities:
STUDY OBJECTIVE: To evaluate the influence of nasal oxygen (O(2)) administration on the duration of arterial oxygen saturation (SpO(2)) >or=95% during simulated difficult laryngoscopy in obesepatients. DESIGN: Prospective, randomized, controlled trial. SETTING: University hospital. PATIENTS: 30 obesemen undergoing general anesthesia. INTERVENTIONS: After thorough preoxygenation, and using total intravenous anesthesia, simulated difficult laryngoscopy was performed, with half the patients receiving additional nasal O(2) during apnea. MEASUREMENTS: Duration of SpO(2) >or=95% was measured up to a maximum of 6 minutes. Lowest SpO(2) values and time to regain 100% SpO(2) (resaturation time) also were recorded. MAIN RESULTS: Nasal O(2) administration was associated with significant prolongation of SpO(2) >or=95% time (5.29 +/- 1.02 vs. 3.49 +/- 1.33 min, mean +/- SD), a significant increase in patients with SpO(2) >or=95% apnea at 6 minutes (8 vs. one pt), and significantly higher minimum SpO(2) (94.3 +/- 4.4% vs. 87.7 +/- 9.3%). Resaturation times were no different between the groups. CONCLUSIONS: Nasal O(2) administration is associated with significant increases in frequency and duration of SpO(2) >or=95%, and higher minimum SpO(2) during prolonged laryngoscopy in obesepatients. (c) 2010 Elsevier Inc. All rights reserved.
Authors: Margaret M Parker; Gabrielle Nuthall; Calvin Brown; Katherine Biagas; Natalie Napolitano; Lee A Polikoff; Dennis Simon; Michael Miksa; Eleanor Gradidge; Jan Hau Lee; Ashwin S Krishna; David Tellez; Geoffrey L Bird; Kyle J Rehder; David A Turner; Michelle Adu-Darko; Sholeen T Nett; Ashley T Derbyshire; Keith Meyer; John Giuliano; Erin B Owen; Janice E Sullivan; Keiko Tarquinio; Pradip Kamat; Ronald C Sanders; Matthew Pinto; G Kris Bysani; Guillaume Emeriaud; Yuki Nagai; Melissa A McCarthy; Karen H Walson; Paula Vanderford; Anthony Lee; Jesse Bain; Peter Skippen; Ryan Breuer; Sarah Tallent; Vinay Nadkarni; Akira Nishisaki Journal: Pediatr Crit Care Med Date: 2017-04 Impact factor: 3.624
Authors: Matthew W Semler; David R Janz; Robert J Lentz; Daniel T Matthews; Brett C Norman; Tufik R Assad; Raj D Keriwala; Benjamin A Ferrell; Michael J Noto; Andrew C McKown; Emily G Kocurek; Melissa A Warren; Luis E Huerta; Todd W Rice Journal: Am J Respir Crit Care Med Date: 2016-02-01 Impact factor: 21.405
Authors: Tiffany S Moon; Katie Tai; Agnes Kim; Michael X Gonzales; Rachael Lu; Taylor Pak; Katelynn Smith; Joy L Chen; Abu T Minhajuddin; Nwamaka Nnamani; Pamela E Fox; Babatunde Ogunnaike Journal: Obes Surg Date: 2019-12 Impact factor: 4.129