Literature DB >> 20399614

Role of antioxidants in the skin: anti-aging effects.

Hitoshi Masaki1.   

Abstract

Intracellular and extracellular oxidative stress initiated by reactive oxygen species (ROS) advance skin aging, which is characterized by wrinkles and atypical pigmentation. Because UV enhances ROS generation in cells, skin aging is usually discussed in relation to UV exposure. The use of antioxidants is an effective approach to prevent symptoms related to photo-induced aging of the skin. In this review, the mechanisms of ROS generation and ROS elimination in the body are summarized. The effects of ROS generated in the skin and the roles of ROS in altering the skin are also discussed. In addition, the effects of representative antioxidants on the skin are summarized with a focus on skin aging. 2010 Japanese Society for Investigative Dermatology. Published by Elsevier Ireland Ltd. All rights reserved.

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Year:  2010        PMID： 20399614     DOI： 10.1016/j.jdermsci.2010.03.003

Source DB:  PubMed          Journal:  J Dermatol Sci        ISSN： 0923-1811            Impact factor:   4.563


  127 in total

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Review 6.  Anti-oxidative effects of superoxide dismutase 3 on inflammatory diseases.

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Journal:  Rejuvenation Res       Date:  2013-10       Impact factor: 4.663

8.  Sambucus nigra L. ameliorates UVB-induced photoaging and inflammatory response in human skin keratinocytes.

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10.  Synthesis and Spectroscopic Studies of Phenanthroimidazole-Imine Derivatives and Evaluation of Their Antioxidant Activity.

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