OBJECTIVES: Multiple sclerosis (MS) is a chronic multifocal CNS disorder which can affect higher order cognitive processes. Whereas cognitive disturbances in MS are increasingly better characterised, emotional facial expression (EFE) has rarely been tested, despite its importance for adequate social behaviour. PATIENTS AND METHODS: We tested 20 patients with a clinically isolated syndrome suggestive of MS (CIS) or MS and 23 healthy controls (HC) for the ability to differ between emotional facial stimuli, controlling for the influence of depressive mood (ADS-L). We screened for cognitive dysfunction using The Faces Symbol Test (FST). RESULTS: The patients demonstrated significant decreased reaction-times regarding emotion recognition tests compared to HC. However, the results also suggested worse cognitive abilities in the patients. Emotional and cognitive test results were correlated. CONCLUSION: This exploratory pilot study suggests that emotion recognition deficits might be prevalent in MS. However, future studies will be needed to overcome the limitations of this study. Copyright 2010 Elsevier B.V. All rights reserved.
OBJECTIVES:Multiple sclerosis (MS) is a chronic multifocal CNS disorder which can affect higher order cognitive processes. Whereas cognitive disturbances in MS are increasingly better characterised, emotional facial expression (EFE) has rarely been tested, despite its importance for adequate social behaviour. PATIENTS AND METHODS: We tested 20 patients with a clinically isolated syndrome suggestive of MS (CIS) or MS and 23 healthy controls (HC) for the ability to differ between emotional facial stimuli, controlling for the influence of depressive mood (ADS-L). We screened for cognitive dysfunction using The Faces Symbol Test (FST). RESULTS: The patients demonstrated significant decreased reaction-times regarding emotion recognition tests compared to HC. However, the results also suggested worse cognitive abilities in the patients. Emotional and cognitive test results were correlated. CONCLUSION: This exploratory pilot study suggests that emotion recognition deficits might be prevalent in MS. However, future studies will be needed to overcome the limitations of this study. Copyright 2010 Elsevier B.V. All rights reserved.
Authors: Jack Cotter; Joseph Firth; Christian Enzinger; Evangelos Kontopantelis; Alison R Yung; Rebecca Elliott; Richard J Drake Journal: Neurology Date: 2016-09-21 Impact factor: 9.910
Authors: Andrea Mike; Erzsebet Strammer; Mihaly Aradi; Gergely Orsi; Gabor Perlaki; Andras Hajnal; Janos Sandor; Miklos Banati; Eniko Illes; Alexander Zaitsev; Robert Herold; Charles R G Guttmann; Zsolt Illes Journal: PLoS One Date: 2013-12-13 Impact factor: 3.240