Literature DB >> 2039810

A high-performance liquid chromatographic method for the determination of stobadin pharmacokinetics in serum.

L Soltés1, Z Kállay, S Bezek, V Fedelesová.   

Abstract

A high-performance liquid chromatographic method was developed to determine stobadin pharmacokinetics in dog and man. The relative bioavailability of stobadin dipalmitate compared with dihydrochloride was 46.4 per cent in dog. In man peak serum concentrations ranged from 12 to 289 ng ml-1 after a single oral dose of stobadin dipalmitate (0.79 to 2.5 mgkg-1).

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Year:  1991        PMID: 2039810     DOI: 10.1002/bdd.2510120104

Source DB:  PubMed          Journal:  Biopharm Drug Dispos        ISSN: 0142-2782            Impact factor:   1.627


  1 in total

1.  Overview of stobadine bioanalysis: evaluation and application in pharmacokinetics.

Authors:  K Bauerová
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1999 Jul-Sep       Impact factor: 2.441

  1 in total

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