Literature DB >> 20395969

Genome-wide association studies in diverse populations.

Noah A Rosenberg1, Lucy Huang, Ethan M Jewett, Zachary A Szpiech, Ivana Jankovic, Michael Boehnke.   

Abstract

Genome-wide association (GWA) studies have identified a large number of SNPs associated with disease phenotypes. As most GWA studies have been performed in populations of European descent, this Review examines the issues involved in extending the consideration of GWA studies to diverse worldwide populations. Although challenges exist with issues such as imputation, admixture and replication, investigation of a greater diversity of populations could make substantial contributions to the goal of mapping the genetic determinants of complex diseases for the human population as a whole.

Entities:  

Mesh：

Year:  2010        PMID： 20395969      PMCID： PMC3079573          DOI： 10.1038/nrg2760

Source DB:  PubMed          Journal:  Nat Rev Genet        ISSN： 1471-0056            Impact factor:   53.242


  136 in total

1.  A human genome diversity cell line panel.

Authors:  Howard M Cann; Claudia de Toma; Lucien Cazes; Marie-Fernande Legrand; Valerie Morel; Laurence Piouffre; Julia Bodmer; Walter F Bodmer; Batsheva Bonne-Tamir; Anne Cambon-Thomsen; Zhu Chen; J Chu; Carlo Carcassi; Licinio Contu; Ruofu Du; Laurent Excoffier; G B Ferrara; Jonathan S Friedlaender; Helena Groot; David Gurwitz; Trefor Jenkins; Rene J Herrera; Xiaoyi Huang; Judith Kidd; Kenneth K Kidd; Andre Langaney; Alice A Lin; S Qasim Mehdi; Peter Parham; Alberto Piazza; Maria Pia Pistillo; Yaping Qian; Qunfang Shu; Jiujin Xu; S Zhu; James L Weber; Henry T Greely; Marcus W Feldman; Gilles Thomas; Jean Dausset; L Luca Cavalli-Sforza
Journal:  Science       Date:  2002-04-12       Impact factor: 47.728

2.  Inference of population structure using multilocus genotype data: linked loci and correlated allele frequencies.

Authors:  Daniel Falush; Matthew Stephens; Jonathan K Pritchard
Journal:  Genetics       Date:  2003-08       Impact factor: 4.562

3.  The allele frequency spectrum in genome-wide human variation data reveals signals of differential demographic history in three large world populations.

Authors:  Gabor T Marth; Eva Czabarka; Janos Murvai; Stephen T Sherry
Journal:  Genetics       Date:  2004-01       Impact factor: 4.562

Review 4.  Prospects for admixture mapping of complex traits.

Authors:  Paul M McKeigue
Journal:  Am J Hum Genet       Date:  2004-11-11       Impact factor: 11.025

5.  Potential etiologic and functional implications of genome-wide association loci for human diseases and traits.

Authors:  Lucia A Hindorff; Praveen Sethupathy; Heather A Junkins; Erin M Ramos; Jayashri P Mehta; Francis S Collins; Teri A Manolio
Journal:  Proc Natl Acad Sci U S A       Date:  2009-05-27       Impact factor: 11.205

6.  SNP imputation in association studies.

Authors:  Eran Halperin; Dietrich A Stephan
Journal:  Nat Biotechnol       Date:  2009-04       Impact factor: 54.908

7.  Personal genomes: The case of the missing heritability.

Authors:  Brendan Maher
Journal:  Nature       Date:  2008-11-06       Impact factor: 49.962

8.  Mapping human genetic diversity in Asia.

Authors:  Mahmood Ameen Abdulla; Ikhlak Ahmed; Anunchai Assawamakin; Jong Bhak; Samir K Brahmachari; Gayvelline C Calacal; Amit Chaurasia; Chien-Hsiun Chen; Jieming Chen; Yuan-Tsong Chen; Jiayou Chu; Eva Maria C Cutiongco-de la Paz; Maria Corazon A De Ungria; Frederick C Delfin; Juli Edo; Suthat Fuchareon; Ho Ghang; Takashi Gojobori; Junsong Han; Sheng-Feng Ho; Boon Peng Hoh; Wei Huang; Hidetoshi Inoko; Pankaj Jha; Timothy A Jinam; Li Jin; Jongsun Jung; Daoroong Kangwanpong; Jatupol Kampuansai; Giulia C Kennedy; Preeti Khurana; Hyung-Lae Kim; Kwangjoong Kim; Sangsoo Kim; Woo-Yeon Kim; Kuchan Kimm; Ryosuke Kimura; Tomohiro Koike; Supasak Kulawonganunchai; Vikrant Kumar; Poh San Lai; Jong-Young Lee; Sunghoon Lee; Edison T Liu; Partha P Majumder; Kiran Kumar Mandapati; Sangkot Marzuki; Wayne Mitchell; Mitali Mukerji; Kenji Naritomi; Chumpol Ngamphiw; Norio Niikawa; Nao Nishida; Bermseok Oh; Sangho Oh; Jun Ohashi; Akira Oka; Rick Ong; Carmencita D Padilla; Prasit Palittapongarnpim; Henry B Perdigon; Maude Elvira Phipps; Eileen Png; Yoshiyuki Sakaki; Jazelyn M Salvador; Yuliana Sandraling; Vinod Scaria; Mark Seielstad; Mohd Ros Sidek; Amit Sinha; Metawee Srikummool; Herawati Sudoyo; Sumio Sugano; Helena Suryadi; Yoshiyuki Suzuki; Kristina A Tabbada; Adrian Tan; Katsushi Tokunaga; Sissades Tongsima; Lilian P Villamor; Eric Wang; Ying Wang; Haifeng Wang; Jer-Yuarn Wu; Huasheng Xiao; Shuhua Xu; Jin Ok Yang; Yin Yao Shugart; Hyang-Sook Yoo; Wentao Yuan; Guoping Zhao; Bin Alwi Zilfalil
Journal:  Science       Date:  2009-12-11       Impact factor: 47.728

9.  Exploring population genetic models with recombination using efficient forward-time simulations.

Authors:  Badri Padhukasahasram; Paul Marjoram; Jeffrey D Wall; Carlos D Bustamante; Magnus Nordborg
Journal:  Genetics       Date:  2008-04       Impact factor: 4.562

Review 10.  Linkage disequilibrium--understanding the evolutionary past and mapping the medical future.

Authors:  Montgomery Slatkin
Journal:  Nat Rev Genet       Date:  2008-06       Impact factor: 53.242
View more
  269 in total

1.  Consistency of genome-wide associations across major ancestral groups.

Authors:  Evangelia E Ntzani; George Liberopoulos; Teri A Manolio; John P A Ioannidis
Journal:  Hum Genet       Date:  2011-12-20       Impact factor: 4.132

2.  Crohn's disease risk alleles on the NOD2 locus have been maintained by natural selection on standing variation.

Authors:  Shigeki Nakagome; Shuhei Mano; Lukasz Kozlowski; Janusz M Bujnicki; Hiroki Shibata; Yasuaki Fukumaki; Judith R Kidd; Kenneth K Kidd; Shoji Kawamura; Hiroki Oota
Journal:  Mol Biol Evol       Date:  2012-01-12       Impact factor: 16.240

Review 3.  Assessing gene-gene interactions in pharmacogenomics.

Authors:  Hsien-Yuan Lane; Guochuan E Tsai; Eugene Lin
Journal:  Mol Diagn Ther       Date:  2012-02-01       Impact factor: 4.074

4.  2011 Presidential Address: from classroom to courtroom to clinic-closing the gaps in human genetics education.

Authors:  Lynn B Jorde
Journal:  Am J Hum Genet       Date:  2012-03-09       Impact factor: 11.025

5.  Mapping rare and common causal alleles for complex human diseases.

Authors:  Soumya Raychaudhuri
Journal:  Cell       Date:  2011-09-30       Impact factor: 41.582

Review 6.  Towards identifying genes underlying ecologically relevant traits in Arabidopsis thaliana.

Authors:  Joy Bergelson; Fabrice Roux
Journal:  Nat Rev Genet       Date:  2010-12       Impact factor: 53.242

Review 7.  Fine-scale population structure and the era of next-generation sequencing.

Authors:  Brenna M Henn; Simon Gravel; Andres Moreno-Estrada; Suehelay Acevedo-Acevedo; Carlos D Bustamante
Journal:  Hum Mol Genet       Date:  2010-09-28       Impact factor: 6.150

8.  An Exome-Wide Association Study Identifies New Susceptibility Loci for Age of Smoking Initiation in African- and European-American Populations.

Authors:  Keran Jiang; Zhongli Yang; Wenyan Cui; Kunkai Su; Jennie Z Ma; Thomas J Payne; Ming D Li
Journal:  Nicotine Tob Res       Date:  2019-05-21       Impact factor: 4.244

9.  Genetic mutations in African patients with atrial fibrillation: Rationale and design of the Study of Genetics of Atrial Fibrillation in an African Population (SIGNAL).

Authors:  Gerald S Bloomfield; Tecla M Temu; Constantine O Akwanalo; Peng-Sheng Chen; Wilfred Emonyi; Susan R Heckbert; Myra M Koech; Imran Manji; Changyu Shen; Matteo Vatta; Eric J Velazquez; Jennifer Wessel; Sylvester Kimaiyo; Thomas S Inui
Journal:  Am Heart J       Date:  2015-06-14       Impact factor: 4.749

10.  Positive Emotion Regulation and Psychopathology: A Transdiagnostic Cultural Neuroscience Approach.

Authors:  Lisa A Hechtman; Hannah Raila; Joan Y Chiao; June Gruber
Journal:  J Exp Psychopathol       Date:  2013-05-13
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.