Literature DB >> 20395697

Osteopontin in cardiovascular disease: a potential therapeutic target.

Alfonso H Waller1, Monica Sanchez-Ross, Edo Kaluski, Marc Klapholz.   

Abstract

Osteopontin (OPN), also known as 44kDa bone phosphoprotein, sialoprotein I, secreted phosphoprotein I, 2ar, uropontin, and early T-lymphocyte activation-1 (Eta-1), is a multifunctional protein. OPN has been found to be expressed in various cell types and species with many physiologic and pathologic functions. OPN has emerged as a potential biomarker and mediator in cardiovascular disease. In this review, we will discuss the roles of OPN in cardiovascular disease, specifically in vascular and valvular heart disease, myocardial infarction and heart failure.

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Year:  2010        PMID: 20395697     DOI: 10.1097/CRD.0b013e3181cfb646

Source DB:  PubMed          Journal:  Cardiol Rev        ISSN: 1061-5377            Impact factor:   2.644


  30 in total

Review 1.  Matricellular proteins in drug delivery: Therapeutic targets, active agents, and therapeutic localization.

Authors:  Andrew J Sawyer; Themis R Kyriakides
Journal:  Adv Drug Deliv Rev       Date:  2016-01-04       Impact factor: 15.470

2.  Serum level of osteopontin as an inflammatory marker does not indicate disease activity or responsiveness to therapeutic treatments in patients with rheumatoid arthritis.

Authors:  Hye-In Ji; Sang-Hoon Lee; Ran Song; Hyung-In Yang; Yeon-Ah Lee; Seung-Jae Hong; Somi Kim; Yong-Beom Park; Soo-Kon Lee; Myung Chul Yoo; Kyoung Soo Kim
Journal:  Clin Rheumatol       Date:  2013-09-01       Impact factor: 2.980

3.  Osteopontin-stimulated expression of matrix metalloproteinase-9 causes cardiomyopathy in the mdx model of Duchenne muscular dystrophy.

Authors:  Saurabh Dahiya; Srikanth Givvimani; Shephali Bhatnagar; Natia Qipshidze; Suresh C Tyagi; Ashok Kumar
Journal:  J Immunol       Date:  2011-08-01       Impact factor: 5.422

4.  Na(+)/H (+) exchanger isoform 1 induced osteopontin expression in cardiomyocytes involves NFAT3/Gata4.

Authors:  Mohamed Mlih; Nabeel Abdulrahman; Alain-Pierre Gadeau; Iman A Mohamed; Maiy Jaballah; Fatima Mraiche
Journal:  Mol Cell Biochem       Date:  2015-03-11       Impact factor: 3.396

5.  Isotretinoin increased carotid intima-media thickness in acne patients.

Authors:  A Saklamaz; B Uyar; M Yalcin; H Cengiz
Journal:  Hippokratia       Date:  2016 Jan-Mar       Impact factor: 0.471

6.  Expression profile of the matricellular protein osteopontin in primary open-angle glaucoma and the normal human eye.

Authors:  Uttio Roy Chowdhury; Seung-Youn Jea; Dong-Jin Oh; Douglas J Rhee; Michael P Fautsch
Journal:  Invest Ophthalmol Vis Sci       Date:  2011-08-16       Impact factor: 4.799

7.  Osteopontin in Vascular Disease.

Authors:  Zoe Shin Yee Lok; Alicia N Lyle
Journal:  Arterioscler Thromb Vasc Biol       Date:  2019-04       Impact factor: 8.311

8.  Macrophages are required for neonatal heart regeneration.

Authors:  Arin B Aurora; Enzo R Porrello; Wei Tan; Ahmed I Mahmoud; Joseph A Hill; Rhonda Bassel-Duby; Hesham A Sadek; Eric N Olson
Journal:  J Clin Invest       Date:  2014-02-24       Impact factor: 14.808

9.  Cyclic Strain and Hypertension Increase Osteopontin Expression in the Aorta.

Authors:  Christa Caesar; Alicia N Lyle; Giji Joseph; Daiana Weiss; Fadi M F Alameddine; Bernard Lassègue; Kathy K Griendling; W Robert Taylor
Journal:  Cell Mol Bioeng       Date:  2016-12-27       Impact factor: 2.321

10.  Glucose-Dependent Insulinotropic Peptide in the High-Normal Range Is Associated With Increased Carotid Intima-Media Thickness.

Authors:  Amra Jujić; Peter M Nilsson; Naeimeh Atabaki-Pasdar; Anna Dieden; Tiinamaija Tuomi; Paul W Franks; Jens Juul Holst; Signe Sørensen Torekov; Susana Ravassa; Javier Díez; Margaretha Persson; Emma Ahlqvist; Olle Melander; Maria F Gomez; Leif Groop; Martin Magnusson
Journal:  Diabetes Care       Date:  2020-11-18       Impact factor: 19.112

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