Photocatalytic degradation kinetics and mechanism of environmental pharmaceuticals in aqueous suspension of TiO2: a case of beta-blockers.

This study investigated the photocatalytic degradation of three beta-blockers in TiO(2) suspensions. The disappearance of the compounds followed pseudo-first-order kinetics according to the Langmuir-Hinshelwood model and the rate constants were 0.075, 0.072 and 0.182 min(-1) for atenolol, metoprolol and propranolol, respectively. After 240 min irradiation, the reaction intermediates were completely mineralized to CO(2) and the nitrogen was predominantly as NH(4)(+). The influence of initial pH and beta-blocker concentration on the kinetics was also studied. From adsorption studies it appears that the photocatalytic degradation occurred mainly on the surface of TiO(2). Further studies indicated that surface reaction with OH radical was principally responsible for the degradation of these three beta-blockers. The major degradation intermediates were identified by HPLC/MS analysis. Cleavage of the side chain and the addition of the hydroxyl group to the parent compounds were found to be the two main degradation pathways for all three beta-blockers. 2010 Elsevier B.V. All rights reserved.